Melanogenesis is a complex process in which melanin is synthesized in melanocytes and
transported to keratinocytes, which involves multiple genes and signaling pathways …

Simple Summary Cutaneous melanoma represents the most aggressive form of skin cancer
and its occurrence, development, and progression are based on the accumulation of several …

Simple Summary Although rare, uveal melanoma (UM) is the most common cancer that
develops inside adult eyes. The prognosis is poor, since 50% of patients will develop lethal …

Advances in melanoma research have unveiled critical insights into its genetic and
molecular landscape, leading to significant therapeutic innovations. This review explores the …

Cutaneous melanoma is a lethal disease, even when diagnosed in advanced stages.
Although recent progress in biology and treatment has dramatically improved survival rates …

Melanoma cells are notorious for their high plasticity and ability to switch back and forth
between various melanoma cell states, enabling the adaptation to sub-optimal conditions …

Malignant melanoma is the most lethal type of skin cancer with high rates of mortality.
Although current treatment options provide a short-clinical benefit, acquired-drug resistance …

A number of novel anticancer drugs have been developed in recent years. However, the
mortality of cancer patients remains high because of the emergence of drug resistance. It …

Melanoma is a life-threatening form of skin cancer with an elevated risk of metastasis and
high mortality rates. The prognosis and clinical outcomes of cancer immunotherapy in …

Our collective understanding of melanoma genomics has rapidly expanded in the past
decade, bringing great promise to patients affected with the most severe and aggressive …