Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems

O Tacar, P Sriamornsak, CR Dass - Journal of pharmacy and …, 2013 - academic.oup.com
Objectives The frontline drug doxorubicin has been used for treating cancer for over 30
years. While providing a cure in select cases, doxorubicin causes toxicity to most major …

Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications

Y Li, J Rodrigues, H Tomás - Chemical Society Reviews, 2012 - pubs.rsc.org
Injectable hydrogels with biodegradability have in situ formability which in vitro/in vivo allows
an effective and homogeneous encapsulation of drugs/cells, and convenient in vivo surgical …

[HTML][HTML] Advances in haemostatic sponges: Characteristics and the underlying mechanisms for rapid haemostasis

A Nepal, HDN Tran, NT Nguyen, HT Ta - Bioactive Materials, 2023 - Elsevier
In traumatized patients, the primary cause of mortality is uncontrollable continuous bleeding
and unexpected intraoperative bleeding which is likely to increase the risk of complications …

[图书][B] Chitin, chitosan, oligosaccharides and their derivatives: biological activities and applications

SK Kim - 2010 - books.google.com
Providing comprehensive coverage of the biological activities and industrial applications of
Chitin, Chitosan, oligosaccharides, and their derivatives, this book presents a balance of …

Thermosensitive polymeric hydrogels as drug delivery systems

C Gong, T Qi, X Wei, Y Qu, Q Wu… - Current medicinal …, 2013 - ingentaconnect.com
Thermosensitive hydrogels are very important biomaterials used in drug delivery systems
(DDSs), which gained increasing attention of researchers. Thermosensitive hydrogels have …

Thermosensitive Chitosan‐β‐Glycerophosphate Hydrogels as Targeted Drug Delivery Systems: An Overview on Preparation and Their Applications

P Rahmanian-Devin… - Advances in …, 2021 - Wiley Online Library
Today, with the advances in technology and science, more advanced drug delivery
formulations are required. One of these new systems is an intelligent hydrogel. These …

A chitosan/β-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer

S Kim, SK Nishimoto, JD Bumgardner, WO Haggard… - Biomaterials, 2010 - Elsevier
We report here the development of a chitosan/β-glycerophosphate (Ch/β-GP) thermo-
sensitive gel to deliver ellagic acid (EA) for cancer treatment. The properties of the Ch/β-GP …

Concepts for developing physical gels of chitosan and of chitosan derivatives

P Sacco, F Furlani, G De Marzo, E Marsich, S Paoletti… - Gels, 2018 - mdpi.com
Chitosan macro-and micro/nano-gels have gained increasing attention in recent years,
especially in the biomedical field, given the well-documented low toxicity, degradability, and …

[HTML][HTML] Chitosan/TPP microparticles obtained by microemulsion method applied in controlled release of heparin

AF Martins, DM de Oliveira, AGB Pereira… - International journal of …, 2012 - Elsevier
This work deals with the preparation of chitosan/tripolyphosphate microparticles (CHT/TPP)
using microemulsion system based on water/benzyl alcohol. The morphology of the …

Molecular simulation of pH-dependent diffusion, loading, and release of doxorubicin in graphene and graphene oxide drug delivery systems

M Mahdavi, F Rahmani, S Nouranian - Journal of Materials Chemistry …, 2016 - pubs.rsc.org
In this study, the adsorption of doxorubicin (DOX), an anticancer drug, on pristine graphene
(PG) and graphene oxide (GO) nanocarriers with different surface oxygen densities and in …