Metabolome changes in cerebral ischemia

TH Shin, DY Lee, S Basith, B Manavalan, MJ Paik… - Cells, 2020 - mdpi.com
Cerebral ischemia is caused by perturbations in blood flow to the brain that trigger
sequential and complex metabolic and cellular pathologies. This leads to brain tissue …

Overview of acute ischemic stroke evaluation and management

TF Hasan, H Hasan, RE Kelley - Biomedicines, 2021 - mdpi.com
Stroke is a major contributor to death and disability worldwide. Prior to modern therapy, post-
stroke mortality was approximately 10% in the acute period, with nearly one-half of the …

Neutrophil-to-lymphocyte ratio and symptomatic hemorrhagic transformation in ischemic stroke patients undergoing revascularization

M Świtońska, N Piekuś-Słomka, A Słomka, P Sokal… - Brain Sciences, 2020 - mdpi.com
Objectives: Symptomatic hemorrhagic transformation (sHT) is a life-threatening complication
of acute ischemic stroke (AIS). The early identification of the patients at increased risk of sHT …

Detection, diagnosis and treatment of acute ischemic stroke: current and future perspectives

S Patil, R Rossi, D Jabrah, K Doyle - Frontiers in medical technology, 2022 - frontiersin.org
Stroke is one of the leading causes of disability worldwide. Early diagnosis and treatment of
stroke are important for better clinical outcome. Rapid and accurate diagnosis of stroke …

Stroke‐related epilepsy

AM Feyissa, TF Hasan… - European journal of …, 2019 - Wiley Online Library
Stroke is the cause of about 10% of all epilepsy and 55% of newly diagnosed seizures
among the elderly. Although recent advances in acute stroke therapy have improved …

Incidence, implications, and management of seizures following ischemic and hemorrhagic stroke

JW Doria, PB Forgacs - Current neurology and neuroscience reports, 2019 - Springer
Abstract Purpose of Review In this review, we summarize the recent literature regarding the
incidence and treatment of seizures arising after ischemic and hemorrhagic strokes …

The association between systemic inflammatory markers and post-stroke depression: a prospective stroke cohort

J Hu, L Wang, K Fan, W Ren, Q Wang… - … interventions in aging, 2021 - Taylor & Francis
Objective Inflammation plays an important role in stroke. Many inflammatory markers in
peripheral blood are proved to be associated with stroke severity or prognosis. But few …

Identification of immune-related key genes in the peripheral blood of ischaemic stroke patients using a weighted gene coexpression network analysis and machine …

PF Zheng, LZ Chen, P Liu, HW Pan, WJ Fan… - Journal of Translational …, 2022 - Springer
Background The immune system plays a vital role in the pathological process of ischaemic
stroke. However, the exact immune-related mechanism remains unclear. The current …

Identifying the pattern of immune related cells and genes in the peripheral blood of ischemic stroke

Z Li, Y Cui, J Feng, Y Guo - Journal of Translational Medicine, 2020 - Springer
Background Ischemic stroke (IS) is the second leading cause of death worldwide which is a
serious hazard to human health. Evidence suggests that the immune system plays a key role …

Emerging role of PARP‐1 and PARthanatos in ischemic stroke

S Liu, W Luo, Y Wang - Journal of neurochemistry, 2022 - Wiley Online Library
Cell death is a key feature of neurological diseases, including stroke and neurodegenerative
disorders. Studies in a variety of ischemic/hypoxic mouse models demonstrate that poly …