Gastrointestinal cancer is a worldwide health challenge due to its dramatically increasing
prevalence and as a leading cause of cancer-related mortality. Increasing evidence has …

The aryl hydrocarbon receptor (AhR) interacting protein (AIP) is a ubiquitously expressed,
immunophilin-like protein best known for its role as a co-chaperone in the AhR-AIP-Hsp90 …

Background Endometrial cancer (EC) is the most common cancer of the female reproductive
organs. Despite the good overall prognosis of most low-grade ECs, FIGO I and FIGO II …

A deeper understanding of colorectal cancer (CRC) biology would help to identify specific
early diagnostic markers. Here, we conducted quantitative proteomics on FFPE healthy …

Aryl hydrocarbon receptor-interacting protein (AIP) is a co-chaperone to heat shock proteins
and nuclear receptors. Loss-of-function heterozygote germline mutations lead to …

Introduction Tissue-based proteomic studies of colorectal cancer (CRC) metastasis have
delivered fragmented results, with very few therapeutic targets and prognostic biomarkers …

Conspectus Light is ubiquitously available to probe the structure and dynamics of
biomolecules and biological tissues. Generally, this cannot be done directly with visible light …

SPRY domain-containing protein 7 (SPRYD7) is a barely known protein identified via spatial
proteomics as being upregulated in highly metastatic-to-liver KM12SM colorectal cancer …

Clathrin assembles at the cells' plasma membrane in a multitude of clathrin-coated
structures (CCSs). Among these are flat clathrin lattices (FCLs), alternative clathrin structures …

It is usually considered that only 5% of all pituitary neuroendocrine tumours are due to
inheritable causes. Since this estimate was reported, however, multiple genetic defects …