[HTML][HTML] Tumor hypoxia and radiotherapy: A major driver of resistance even for novel radiotherapy modalities

C Beckers, M Pruschy, I Vetrugno - Seminars in Cancer Biology, 2024 - Elsevier
Hypoxia in solid tumors is an important predictor of poor clinical outcome to radiotherapy.
Both physicochemical and biological processes contribute to a reduced sensitivity of hypoxic …

The tumor radiobiology of SRS and SBRT: are more than the 5 Rs involved?

JM Brown, DJ Carlson, DJ Brenner - International Journal of Radiation …, 2014 - Elsevier
Stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT), also known
as stereotactic ablative radiation therapy (SABR), are rapidly becoming accepted practice for …

The radiobiology of hypofractionation

AE Nahum - Clinical oncology, 2015 - Elsevier
If the α/β ratio is high (eg 10 Gy) for tumour clonogen killing, but low (eg 3 Gy) for late normal
tissue complications, then delivering external beam radiotherapy in a large number (20–30) …

Stereotactic ablative body radiosurgery (SABR) or Stereotactic body radiation therapy (SBRT)

MR Folkert, RD Timmerman - Advanced drug delivery reviews, 2017 - Elsevier
While conventional treatment relies on protracted courses of therapy using relatively small
dose-per-fraction sizes of 1.8–2 Gy, there is substantial evidence gathered over decades …

Targeting myeloid-derived suppressor cells and programmed death ligand 1 confers therapeutic advantage of ablative hypofractionated radiation therapy compared …

J Lan, R Li, LM Yin, L Deng, J Gui, BQ Chen… - International Journal of …, 2018 - Elsevier
Purpose Ablative hypofractionated radiation therapy (AHFRT) presents a therapeutic
advantage compared with conventional fractionated radiation therapy (CFRT) for primary …

New challenges in high-energy particle radiobiology

M Durante - The British journal of radiology, 2014 - academic.oup.com
Densely ionizing radiation has always been a main topic in radiobiology. In fact, α-particles
and neutrons are sources of radiation exposure for the general population and workers in …

What is the ideal radiotherapy dose to treat prostate cancer? A meta-analysis of biologically equivalent dose escalation

NG Zaorsky, JD Palmer, MD Hurwitz, SW Keith… - Radiotherapy and …, 2015 - Elsevier
Purpose To determine if increasing the biologically equivalent dose (BED) via various
radiation fractionation regimens is correlated with clinical outcomes or toxicities for prostate …

The international commission on radiation units and measurements

HG Menzel - Journal of the ICRU, 2012 - journals.sagepub.com
The International Commission on Radiation Units and Measurements - Hans-Georg Menzel,
2012 Skip to main content Scheduled maintenance on Monday, November 20th, with …

[HTML][HTML] Comparison of long-term survival outcomes between stereotactic body radiotherapy and sublobar resection for stage I non-small-cell lung cancer in patients …

Y Matsuo, F Chen, M Hamaji, A Kawaguchi… - European journal of …, 2014 - Elsevier
Background The aim of this study was to perform a survival comparison between stereotactic
body radiotherapy (SBRT) and sublobar resection (SLR) in patients with stage I non-small …

Increasing radiation therapy dose is associated with improved survival in patients undergoing stereotactic body radiation therapy for stage I non–small-cell lung …

M Koshy, R Malik, RR Weichselbaum… - International Journal of …, 2015 - Elsevier
Purpose To determine the comparative effectiveness of different stereotactic body radiation
therapy (SBRT) dosing regimens for early-stage non–small-cell lung cancer, using a large …