Artificial intelligence and pathology: from principles to practice and future applications in histomorphology and molecular profiling
The complexity of diagnostic (surgical) pathology has increased substantially over the last
decades with respect to histomorphological and molecular profiling. Pathology has steadily …
decades with respect to histomorphological and molecular profiling. Pathology has steadily …
Clinical and analytical validation of FoundationOne®CDx, a comprehensive genomic profiling assay for solid tumors
CA Milbury, J Creeden, WK Yip, DL Smith, V Pattani… - PLoS …, 2022 - journals.plos.org
FoundationOne® CDx (F1CDx) is a United States (US) Food and Drug Administration (FDA)-
approved companion diagnostic test to identify patients who may benefit from treatment in …
approved companion diagnostic test to identify patients who may benefit from treatment in …
[HTML][HTML] Molecular profiling in cholangiocarcinoma: a practical guide to next-generation sequencing
Cholangiocarcinomas (CCA) are a heterogeneous group of tumors that are classified as
intrahepatic, perihilar, or distal according to the anatomic location within the biliary tract …
intrahepatic, perihilar, or distal according to the anatomic location within the biliary tract …
Integrating somatic and germline next-generation sequencing into routine clinical oncology practice
Next-generation sequencing (NGS) is rapidly expanding into routine oncology practice.
Genetic variations in both the cancer and inherited genomes are informative for hereditary …
Genetic variations in both the cancer and inherited genomes are informative for hereditary …
Virtual multidisciplinary tumor boards: a narrative review focused on lung cancer
To date, the virtual multidisciplinary tumor boards (vMTBs) are increasingly used to achieve
high-quality treatment recommendations across health-care regions, which expands and …
high-quality treatment recommendations across health-care regions, which expands and …
High‐throughput molecular assays for inclusion in personalised oncology trials–State‐of‐the‐art and beyond
A Edsjö, HG Russnes, J Lehtiö… - Journal of internal …, 2024 - Wiley Online Library
In the last decades, the development of high‐throughput molecular assays has
revolutionised cancer diagnostics, paving the way for the concept of personalised cancer …
revolutionised cancer diagnostics, paving the way for the concept of personalised cancer …
[HTML][HTML] Fighting cancer around the world: A framework for action
Tackling cancer is a major challenge right on the global level. Europe is only the tip of an
iceberg of cancer around the world. Prosperous developed countries share the same …
iceberg of cancer around the world. Prosperous developed countries share the same …
Envisioning the future of precision oncology trials
Precision oncology trials based on cancer biomarkers have the potential to improve
outcomes by guiding the optimal choice of therapies for patients. For this to be truly …
outcomes by guiding the optimal choice of therapies for patients. For this to be truly …
[HTML][HTML] Recommendations for the use of next-generation sequencing and the molecular tumor board for patients with advanced cancer: a report from KSMO and …
Next-generation sequencing (NGS) is becoming essential in the fields of precision oncology.
With implementation of NGS in daily clinic, the needs for continued education, facilitated …
With implementation of NGS in daily clinic, the needs for continued education, facilitated …
Knowledge bases and software support for variant interpretation in precision oncology
Precision oncology is a rapidly evolving interdisciplinary medical specialty. Comprehensive
cancer panels are becoming increasingly available at pathology departments worldwide …
cancer panels are becoming increasingly available at pathology departments worldwide …