Recent updates in nanoscale delivery systems of platinum (IV) antitumor prodrugs
Z Zhou, P Shi, C Wang, Y Sun, C Gao - Coordination Chemistry Reviews, 2024 - Elsevier
Platinum-based anticancer drugs still play a crucial role in the treatment of various solid
tumors such as ovarian, lung, colorectal, bladder, and breast cancer. However, their ability to …
tumors such as ovarian, lung, colorectal, bladder, and breast cancer. However, their ability to …
Current Status of Novel Multifunctional Targeted Pt (IV) Compounds and Their Reductive Release Properties
L Xu, X Kong, X Li, B Zhang, Y Deng, J Wang, C Duan… - Molecules, 2024 - mdpi.com
Platinum-based drugs are widely used in chemotherapy for various types of cancer and are
considered crucial. Tetravalent platinum (Pt (IV)) compounds have gained significant …
considered crucial. Tetravalent platinum (Pt (IV)) compounds have gained significant …
Biotin and boron-dipyrromethene-tagged platinum (IV) prodrug for cellular imaging and mito-targeted photocytotoxicity in red light
A platinum (IV) prodrug, cis, cis, trans-[Pt (NH3) 2Cl2 (biotin)(L)](1), derived from cisplatin,
where HL is the PEGylated red-light active boron-dipyrromethene (BODIPY) ligand, was …
where HL is the PEGylated red-light active boron-dipyrromethene (BODIPY) ligand, was …
Advances and perspectives in phototherapy-based combination therapy for cancer treatment
J Yi, L Liu, W Gao, J Zeng, Y Chen, E Pang… - Journal of Materials …, 2024 - pubs.rsc.org
Phototherapy, including photothermal therapy (PTT) and photodynamic therapy (PDT), has
the advantages of spatiotemporal selectivity, non-invasiveness, and negligible drug …
the advantages of spatiotemporal selectivity, non-invasiveness, and negligible drug …
Riboflavin Crystals with Extremely High Water Solubility
PV Krikunova, ER Tolordava… - … Applied Materials & …, 2024 - ACS Publications
New insights into the unique biochemical properties of riboflavin (Rf), also known as vitamin
B2, are leading to the development of its use not only as a vitamin supplement but also as a …
B2, are leading to the development of its use not only as a vitamin supplement but also as a …
Biotin–Pt (IV)–Ru (II)–Boron–Dipyrromethene Prodrug as “Platin Bullet” for Targeted Chemo-and Photodynamic Therapy
Using the principle of “Magic Bullet”, a cisplatin-derived platinum (IV) prodrug
heterobimetallic Pt (IV)–Ru (II) complex, cis, cis, trans-[Pt (NH3) 2Cl2 {Ru (tpy–BODIPY)(tpy …
heterobimetallic Pt (IV)–Ru (II) complex, cis, cis, trans-[Pt (NH3) 2Cl2 {Ru (tpy–BODIPY)(tpy …
Computational Assessment of Novel Ruthenium Phenoxazine‐Based Complexes as Photosensitizers in Photodynamic Therapy
A computational examination of two new polypyridyl ruthenium complexes, containing
meldola blue (MDB) and nile blue (NB) chromophores, is here reported in order to assess …
meldola blue (MDB) and nile blue (NB) chromophores, is here reported in order to assess …
Light-Responsive Pt (IV) Prodrugs with Controlled Photoactivation and Low Dark Toxicity
D Spector, A Bubley, A Zharova, V Bykusov… - ACS Applied Bio …, 2024 - ACS Publications
Light-induced release of cisplatin from Pt (IV) prodrugs represents a promising approach for
precise control over the antiproliferative activity of Pt-based chemotherapeutic drugs. This …
precise control over the antiproliferative activity of Pt-based chemotherapeutic drugs. This …
Photoactivated full-API nanodrug (FAND): harnessing transition metal complexes and MTH1 inhibitor for enhanced DNA damage in cancer cells
H Zhu, M Cui, Q Tang, H Zhao, P Zhang, S Zeng… - Biomaterials …, 2024 - pubs.rsc.org
The effectiveness of photodynamic therapy (PDT) has been greatly restricted by the hypoxic
tumor microenvironment and the susceptible resistance of monotherapy. Although …
tumor microenvironment and the susceptible resistance of monotherapy. Although …
[HTML][HTML] Photoimmunotherapy for cancer treatment based on organic small molecules: Recent strategies and future directions
D Zhao, X Wen, J Wu, F Chen - Translational Oncology, 2024 - Elsevier
Photodynamic therapy (PDT) is considered as a promising anticancer approach, owning to
its high efficiency and spatiotemporal selectivity. Ample evidence indicated that PDT can …
its high efficiency and spatiotemporal selectivity. Ample evidence indicated that PDT can …