Background Bioinspired multienzyme engineering provides strong technical support for
enhancing food quality, safety, and nutrition. Summarizing and examining its applications …

Manipulating protein architectures beyond genetic control has attracted widespread
attention. Catcher/Tag systems enable highly specific conjugation of proteins in vivo and in …

Controlling chemical reactivity has been the central theme in chemistry. Herein, we review
the recent progress on the development of genetically encoded protein coupling reactions …

Comprehensive Summary Chemical topology refers to the three‐dimensional arrangement
(ie., connectivity and spatial relationship) of a molecule's constituent atoms and bonds. The …

Genetically encoded covalent peptide tagging tools such as the SpyTag/SpyCatcher
reactive pair, have been demonstrated versatile and useful for protein modification. Herein …

The surprising discovery of intramolecular isopeptide bonds within Gram-positive bacteria
pili and surface adhesins gave rise to the development of a new type of protein conjugation …