Bioactive molecules derived from snake venoms with therapeutic potential for the treatment of thrombo-cardiovascular disorders associated with COVID-19
F Cherifi, F Laraba-Djebari - The protein journal, 2021 - Springer
As expected, several new variants of Severe Acute Respiratory Syndrome-CoronaVirus-2
(SARS-CoV-2) emerged and have been detected around the world throughout this …
(SARS-CoV-2) emerged and have been detected around the world throughout this …
State-of-the-art review-A review on snake venom-derived antithrombotics: Potential therapeutics for COVID-19-associated thrombosis?
B Kalita, AJ Saviola, SP Samuel… - International Journal of …, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent
responsible for the Coronavirus Disease-2019 (COVID-19) pandemic, has infected over 185 …
responsible for the Coronavirus Disease-2019 (COVID-19) pandemic, has infected over 185 …
A fingerprint of plasma proteome alteration after local tissue damage induced by Bothrops leucurus snake venom in mice
J dos Santos Cavalcante, CAS de Almeida… - Journal of …, 2022 - Elsevier
Bothrops spp. is responsible for about 70% of snakebites in Brazil, causing a diverse and
complex pathophysiological condition. Bothrops leucurus is the main species of medical …
complex pathophysiological condition. Bothrops leucurus is the main species of medical …
[HTML][HTML] State-of-the-art review of snake venom phosphodiesterases (svPDEs)
Phosphodiesterases (PDEs) constitute an enzyme group able to hydrolyze nucleic acids as
well as some second messengers. Due to this ability and their expression in several human …
well as some second messengers. Due to this ability and their expression in several human …
Isolation and characterization of the first phosphodiesterase (Bj-PDE) from the venom of Bothrops jararacussu snake
FG Amorim, TA Silva, G de Oliveira Almeida… - International Journal of …, 2023 - Elsevier
Phosphodiesterases are exonucleases that sequentially hydrolyse phosphodiester bonds of
polynucleotides from the 3′-end and release 5-mononucleotides. After more than one …
polynucleotides from the 3′-end and release 5-mononucleotides. After more than one …
Identification of purinergic system components in the venom of Bothrops mattogrossensis and the inhibitory effect of specioside extracted from Tabebuia aurea
DA Dias, KF Souza de Souza, ISB Moslaves… - Purinergic …, 2024 - Springer
Snake bites are a severe problem in the countryside of Brazil and are usually attributed to
snakes of the genera Bothrops, Crotalus, and Lachesis. Snake venom can release …
snakes of the genera Bothrops, Crotalus, and Lachesis. Snake venom can release …
Structural, biochemical characterization and molecular mechanism of Cerastokunin: A new Kunitz-type peptide with potential inhibition of thrombin, factor Xa and …
N Saghour, F Chérifi, S Saoud, Y Zebbiche… - The Protein …, 2024 - Springer
The current investigation focused on separating Cerastes cerastes venom to produce the
first Kunitz-type peptide. Based on its anti-trypsin effect, Cerastokunin, a 7.75 kDa peptide …
first Kunitz-type peptide. Based on its anti-trypsin effect, Cerastokunin, a 7.75 kDa peptide …
Therapeutic Outcome of Anti-inflammatory and Antioxidative Medicines on the Dermonecrotic Activity of Cerastes cerastes Venom
A Khelfi, H Oussedik-Oumehdi, F Laraba-Djebari - Inflammation, 2022 - Springer
Envenomation by Cerastes cerastes often results in local dermonecrotic lesions. While
immunotherapy is effective in reversing systemic symptoms, this strategy remains deficient in …
immunotherapy is effective in reversing systemic symptoms, this strategy remains deficient in …