This mini-review summarizes key points from the Clark Sawin Memorial Lecture on the
History of Estrogen delivered at Endo 2018 and focuses on the rationales and motivation …

Puberty is a complex biological event that requires maturation of the reproductive
neuroendocrine axis and subsequent initiation of high-frequency, episodic release of GnRH …

Gonadotropin-releasing hormone (GnRH) is the master regulator of the hypothalamic-
pituitary-gonadal (HPG) axis, and therefore of fertility and reproduction. The release pattern …

Puberty is a complex physiological process in females that requires maturation of the
reproductive neuroendocrine system and subsequent initiation of high-frequency, episodic …

Simple Summary Mistiming of puberty onset has negative consequences for humans and
livestock. Puberty depends on increased brain secretion of gonadotrophin-releasing …

Pubertal attainment is an intricate biological process that involves maturation of the
reproductive neuroendocrine axis and increased pulsatile release of gonadotropin …

The activation of the hypothalamic–pituitary axis is critical for the initiation and maintenance
of reproductive cycles in pigs and is influenced by a number of factors, such as nutrition …

The discovery of the kisspeptin (Kp) system stirred a burst of research in the field of
reproductive neuroendocrinology. In the last 15 yr, the organization and activity of the …

Animal models remain essential to understand the fundamental mechanisms of physiology
and pathology. Particularly, the complex and dynamic nature of neuroendocrine cells of the …

Background: Neuronal intermediates that communicate estrogen and progesterone
feedback to gonadotropin-releasing hormone (GnRH) neurons are essential for modulating …