[HTML][HTML] Metabolic Side Effects from Antipsychotic Treatment with Clozapine Linked to Aryl Hydrocarbon Receptor (AhR) Activation

K Fehsel - Biomedicines, 2024 - mdpi.com
Metabolic syndrome (MetS) is the most common adverse drug reaction from psychiatric
pharmacotherapy. Neuroreceptor blockade by the antipsychotic drug clozapine induces …

Hepatocyte-specific NR5A2 deficiency induces pyroptosis and exacerbates non-alcoholic steatohepatitis by downregulating ALDH1B1 expression

R Zhao, Z Guo, K Lu, Q Chen, F Riaz, Y Zhou… - Cell Death & …, 2024 - nature.com
Nonalcoholic steatohepatitis (NASH) is a prevalent chronic disease, yet its exact
mechanisms and effective treatments remain elusive. Nuclear receptor subfamily 5 group A …

Psychosis and autism spectrum disorder: a special issue of Molecular Psychiatry

J Licinio, ML Wong - Molecular Psychiatry, 2023 - nature.com
In this issue of Molecular Psychiatry, we have multiple articles that present exciting
advances in psychosis and autism spectrum disorder (ASD). We start with interesting …

NR5A2 promotes epithelial-to-mesenchymal transition in renal fibrosis by targeting MMP25 transcription

G Chen, W Shan, Y Chen, W Wang, X Li - 2024 - researchsquare.com
Epithelial-to-mesenchymal transition (EMT) is crucial for the progression of renal
tubulointerstitial fibrosis, typically leading to end-stage renal failure. The role of Nuclear …

Metabolinio sindromo tarp psichikos sutrikimais sergančiųjų, besigydančių psichiatrijos ligoninėje, paplitimas

JP Druta - 2024 - epublications.vu.lt
Abstract [eng] Metabolic syndrome is a dysfunction in metabolism of the body associated
with hypertension, altered glucose tolerance, enlarged body mass and dyslipidemia. The …