Plague vaccine development: current research and future trends

SK Verma, U Tuteja - Frontiers in immunology, 2016 - frontiersin.org
Plague is one of the world's most lethal human diseases caused by Yersinia pestis, a Gram-
negative bacterium. Despite overwhelming studies for many years worldwide, there is no …

[HTML][HTML] Deliberate release: Plague–A review

I Ansari, G Grier, M Byers - Journal of biosafety and biosecurity, 2020 - Elsevier
Yersinia pestis is the causative agent of plague and is considered one of the most likely
pathogens to be used as a bioweapon. In humans, plague is a severe clinical infection that …

The Natural and Clinical History of Plague: From the Ancient Pandemics to Modern Insights

A Bennasar-Figueras - Microorganisms, 2024 - mdpi.com
The human pathogen Yersinia pestis is responsible for bubonic, septicemic, and pneumonic
plague. A deeply comprehensive overview of its historical context, bacteriological …

Protection Elicited by Attenuated Live Yersinia pestis Vaccine Strains against Lethal Infection with Virulent Y. pestis

CK Cote, SS Biryukov, CP Klimko, JL Shoe, M Hunter… - Vaccines, 2021 - mdpi.com
The etiologic agent of plague, Yersinia pestis, is a globally distributed pathogen which
poses both a natural and adversarial threat. Due largely to the rapid course and high …

Progress on plague vaccine development

JA Rosenzweig, O Jejelowo, J Sha, TE Erova… - Applied microbiology …, 2011 - Springer
Yersinia pestis (YP), the gram-negative plague bacterium, has shaped human history unlike
any other pathogen known to mankind. YP (transmitted by the bite of an infected flea) …

Robust Th1 cellular and humoral responses generated by the Yersinia pestis rF1-V subunit vaccine formulated to contain an agonist of the CD137 pathway do not …

W Bowen, L Batra, AR Pulsifer, ES Yolcu, MB Lawrenz… - Vaccine, 2019 - Elsevier
Yersinia pestis is the causative agent of plague and is a re-emerging pathogen that also has
the potential as a biological weapon, necessitating the development of a preventive vaccine …

Hybrid viral vectors for vaccine and antibody production in plants

V Yusibov, S J. Streatfield, N Kushnir… - Current …, 2013 - benthamdirect.com
Plants have a demonstrated potential for large-scale, rapid production of recombinant
proteins for diverse product applications, including subunit vaccines and monoclonal …

[HTML][HTML] Enhanced Systemic and Mucosal Immune Responses to Haemophilus parasuis by Intranasal Administration of Lactic-Co-Glycolic Acid Microspheres

T Lei, T Dai, L Zhuang, Y Liu, X Li, C Huang, X Zheng - Vaccines, 2024 - mdpi.com
Swine Glasser's disease, instigated by Haemophilus parasuis (H. parasuis), is a significant
bacterial infection that causes substantial economic losses in pig farming operations. The …

Multiple Antigen Peptide Containing B and T Cell Epitopes of F1 Antigen of Yersinia pestis Showed Enhanced Th1 Immune Response in Murine Model

R Ali, RA Naqvi, S Kumar, AA Bhat… - … Journal of Immunology, 2013 - Wiley Online Library
Yersinia pestis is a facultative bacterium that can survive and proliferate inside host
macrophages and cause bubonic, pneumonic and systemic infection. Apart from humoral …

Molecular bases of vaccine-prevention of plague

SV Dentovskaya, PK Kopylov, SA Ivanov… - Molecular Genetics …, 2013 - Springer
The molecular mechanisms of pathogenicity and properties of the formation of specific
plague immunity are reviewed. The history and modern state of vaccine-prevention of …