BACKGROUND: Each year approximately 10million babies do not breathe immediately at
birth, of which about 6million require basic neonatal resuscitation. The major burden is in …

Intrauterine growth restriction (IUGR) is most commonly caused by placental insufficiency, in
response to which the fetus adapts its circulation to preserve oxygen and nutrient supply to …

Objective To determine if it is possible to stabilise the cerebral oxygenation of extremely
preterm infants monitored by cerebral near infrared spectroscopy (NIRS) oximetry. Design …

Each year, 814,000 neonatal deaths and 1.02 million stillbirths result from intrapartum-
related causes, such as intrauterine hypoxia. Almost all of these deaths are in low-and …

The developing brain is particularly vulnerable to reactive oxygen and reactive nitrogen
species–mediated damage because of its high concentrations of unsaturated fatty acids …

Preterm birth with very low birth weight (VLBW,≤ 1500g) is connected to reduced white
matter (WM) integrity in childhood and adolescence. These changes in WM are correlated to …

Despite major advances in obstetrics and neonatal intensive care, preterm infants frequently
suffer from neurological impairments in later life. Preterm and also full-term neonates are …

Aims Hyperoxic breathing might lead to redox imbalance and signaling changes that affect
cerebral function. Paradoxically, hypoxic breathing is also believed to cause oxidative …

Objective To assess whether high and low levels of cerebral oxygenation (regional cerebral
oxygenation [rScO 2]) in infants born at< 32 weeks of gestation were associated with …

Over the last decade, neuroprotective effects of erythropoietin (Epo) and its underlying
mechanisms in terms of signal transduction pathways have been defined and there is a …