[HTML][HTML] Polycystic ovary syndrome: current status and future perspective

EK Barthelmess, RK Naz - Frontiers in bioscience (Elite edition), 2014 - ncbi.nlm.nih.gov
Polycystic ovary syndrome (PCOS) is a widespread reproductive disorder that encompasses
many associated health conditions and has an impact on various metabolic processes …

The “Other” Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo‐Inositol Chemistry)

MP Thomas, SJ Mills, BVL Potter - … Chemie International Edition, 2016 - Wiley Online Library
Cell signaling via inositol phosphates, in particular via the second messenger myo‐inositol
1, 4, 5‐trisphosphate, and phosphoinositides comprises a huge field of biology. Of the nine …

Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues

M Mathew, S Sivaprakasam, JL Phy… - Bioscience …, 2023 - portlandpress.com
Polycystic ovary syndrome (PCOS) is an endocrine and metabolic disorder in women with
components of significant genetic predisposition and possibly multiple, but not yet clearly …

Partially purified non-polar phytocomponents from Aloe barbadensis Mill. gel restores metabolic and reproductive comorbidities in letrozole-induced polycystic ovary …

A Dey, S Dhadhal, R Maharjan, PS Nagar… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance In India, Kumaryasava, a popular Aloe
barbadensis Mill. gel preparation has therapeutic value in treatment of female reproductive …

A regulatory role of androgen in ovarian steroidogenesis by rat granulosa cells

T Hasegawa, Y Kamada, T Hosoya, S Fujita… - The Journal of steroid …, 2017 - Elsevier
Excess androgen and insulin-like growth factor (IGF)-I in the ovarian follicle has been
suggested to be involved in the pathophysiology of polycystic ovary syndrome (PCOS). Here …

Recent developments in antiandrogens and selective androgen receptor modulators

B Haendler, A Cleve - Molecular and cellular endocrinology, 2012 - Elsevier
The androgens testosterone and dihydrotestosterone play an essential role in the
development and maintenance of primary and secondary male characteristics. Androgens …

Роль мелатонина в развитии гестационного сахарного диабета

ЭК Айламазян, ИИ Евсюкова… - Журнал акушерства и …, 2018 - cyberleninka.ru
В обзоре представлены данные литературы о продукции мелатонина и его роли в
регуляции углеводного обмена, механизмах функциональных связей между …

Diabetes and bone health

M Antonopoulou, G Bahtiyar, MA Banerji, AS Sacerdote - Maturitas, 2013 - Elsevier
The increasing prevalence of diabetes especially type 2 diabetes worldwide is indisputable.
Diabetics suffer increased morbidity and mortality, compared to their non-diabetic …

Incretins modulate progesterone biosynthesis by regulating bone morphogenetic protein activity in rat granulosa cells

Y Nishiyama, T Hasegawa, S Fujita, N Iwata… - The Journal of Steroid …, 2018 - Elsevier
The effects of incretins on ovarian steroidogenesis have not been clarified. In this study, we
investigated the effects of incretins, including GIP and GLP-1, on ovarian steroidogenesis …

Genetic polymorphism of cytochrome P450 2D6 determines oestrogen receptor activity of the major infertility drug clomiphene via its active metabolites

TE Mürdter, R Kerb, M Turpeinen… - Human molecular …, 2012 - academic.oup.com
Clomiphene citrate is the most used drug for the treatment of female infertility, a common
condition in western societies and developing countries. Despite dose escalation, up to 30 …