Hepatocellular carcinoma is among the most lethal and prevalent cancers in the human population. Despite its significance, there is only an elemental understanding of the …
▪ Abstract In this review, recent advances in DNA microarray technology and their applications are examined. The many varieties of DNA microarray or DNA chip devices and …
SS Thorgeirsson, JW Grisham - Nature genetics, 2002 - nature.com
Hepatocarcinogenesis is a slow process during which genomic changes progressively alter the hepatocellular phenotype to produce cellular intermediates that evolve into …
F Castaneda, S Rosin-Steiner… - International journal of …, 2007 - ncbi.nlm.nih.gov
We previously found that ethanol at millimolar level (1 mM) activates the expression of transcription factors with subsequent regulation of apoptotic genes in human hepatocellular …
K Panzitt, MMO Tschernatsch, C Guelly, T Moustafa… - Gastroenterology, 2007 - Elsevier
Background & Aims: Recent studies have highlighted the role of noncoding RNAs (ncRNAs) in carcinogenesis, and suggested that this class of genes might be used as biomarkers in …
The Forkhead box protein M1 (FOXM1) transcription factor is a regulator of myriad biological processes, including cell proliferation, cell cycle progression, cell differentiation, DNA …
JS Lee, IS Chu, J Heo, DF Calvisi, Z Sun… - …, 2004 - Wiley Online Library
We analyzed global gene expression patterns of 91 human hepatocellular carcinomas (HCCs) to define the molecular characteristics of the tumors and to test the prognostic value …
QH Ye, LX Qin, M Forgues, P He, JW Kim, AC Peng… - Nature medicine, 2003 - nature.com
Hepatocellular carcinoma (HCC) is one of the most common and aggressive human malignancies. Its high mortality rate is mainly a result of intra-hepatic metastases. We …