[HTML][HTML] Primary sclerosing cholangitis–a comprehensive review

TH Karlsen, T Folseraas, D Thorburn, M Vesterhus - Journal of hepatology, 2017 - Elsevier
Primary sclerosing cholangitis (PSC) is a rare disorder characterised by multi-focal bile duct
strictures and progressive liver disease. Inflammatory bowel disease is usually present and …

Primary sclerosing cholangitis

JK Dyson, U Beuers, DEJ Jones, AW Lohse, M Hudson - The Lancet, 2018 - thelancet.com
Primary sclerosing cholangitis is a rare, chronic cholestatic liver disease characterised by
intrahepatic or extrahepatic stricturing, or both, with bile duct fibrosis. Inflammation and …

EASL Clinical Practice Guidelines on sclerosing cholangitis

O Chazouilleres, U Beuers, A Bergquist, TH Karlsen… - Journal of …, 2022 - Elsevier
Management of primary or secondary sclerosing cholangitis is challenging. These Clinical
Practice Guidelines have been developed to provide practical guidance on debated topics …

AASLD practice guidance on primary sclerosing cholangitis and cholangiocarcinoma

CL Bowlus, L Arrivé, A Bergquist, M Deneau… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AIH,
autoimmune hepatitis; ALP, alkaline phosphatase; ASIR, age standardized incidence rate; …

ACG clinical guideline: primary sclerosing cholangitis

KD Lindor, KV Kowdley… - Official journal of the …, 2015 - journals.lww.com
Primary sclerosing cholangitis is a chronic cholestatic liver disease that can shorten life and
may require liver transplantation. The cause is unknown, although it is commonly associated …

[PDF][PDF] The nonsteroidal farnesoid X receptor agonist cilofexor (GS‐9674) improves markers of cholestasis and liver injury in patients with primary sclerosing …

M Trauner, A Gulamhusein, B Hameed… - …, 2019 - Wiley Online Library
Primary sclerosing cholangitis (PSC) represents a major unmet medical need. In a phase II
double‐blind, placebo‐controlled study, we tested the safety and efficacy of cilofexor …

[HTML][HTML] norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis

P Fickert, GM Hirschfield, G Denk, HU Marschall… - Journal of …, 2017 - Elsevier
Background & Aim Primary sclerosing cholangitis (PSC) represents a devastating bile duct
disease, currently lacking effective medical therapy. 24-norursodeoxycholic acid (norUDCA) …

Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management

JE Eaton, JA Talwalkar, KN Lazaridis, GJ Gores… - Gastroenterology, 2013 - Elsevier
Primary sclerosing cholangitis (PSC), first described in the mid-1850s, is a complex liver
disease that is heterogeneous in its presentation. PSC is characterized by chronic …

[PDF][PDF] The empirical antibiotic treatment of nosocomial spontaneous bacterial peritonitis: results of a randomized, controlled clinical trial

S Piano, S Fasolato, F Salinas, A Romano… - …, 2016 - Wiley Online Library
Spontaneous bacterial peritonitis (SBP) is a common, life‐threatening complication of liver
cirrhosis. Third‐generation cephalosporins have been considered the first‐line treatment of …

Primary sclerosing cholangitis

KN Lazaridis, NF LaRusso - New England Journal of Medicine, 2016 - Mass Medical Soc
Primary Sclerosing Cholangitis | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …