Discovery of natural anti-inflammatory alkaloids: Potential leads for the drug discovery for the treatment of inflammation

R Bai, C Yao, Z Zhong, J Ge, Z Bai, X Ye, T Xie… - European Journal of …, 2021 - Elsevier
Inflammation is an adaptive response of the immune system to tissue malfunction or
homeostatic imbalance. Corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs) …

β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities

J Dai, W Dan, U Schneider, J Wang - European Journal of Medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …

[HTML][HTML] A review on extraction techniques and therapeutic value of polar bioactives from Asian medicinal herbs: Case study on Orthosiphon aristatus, Eurycoma …

NA Abd Aziz, R Hasham, MR Sarmidi… - Saudi Pharmaceutical …, 2021 - Elsevier
Medicinal plants have gained much interest in the prevention and treatment of common
human disease such as cold and fever, hypertension and postpartum. Bioactive compounds …

Bioactive Constituents from the Roots of Eurycoma longifolia

J Ruan, Z Li, Y Zhang, Y Chen, M Liu, L Han, Y Zhang… - Molecules, 2019 - mdpi.com
Four new phenolic components, eurylophenolosides A (1) and B (2), eurylolignanosides A
(3) and B (4), along with twelve known compounds were isolated from the roots of Eurycoma …

Chemical constituents from the rhizomes of Polygonatum sibiricum Red. and anti-inflammatory activity in RAW264.7 macrophage cells

H Zhao, QL Wang, SB Hou, G Chen - Natural product research, 2019 - Taylor & Francis
Chemical investigation of the rhizomes of Polygonatum sibiricum Red. led to the
identification of 27 constituents. Among them, a total of 16 compounds were obtained from …

Recent advances for alkaloids as botanical pesticides for use in organic agriculture

Y Wu, D Ren, C Gao, J Li, B Du, Z Wang… - International Journal of …, 2021 - Taylor & Francis
Alkaloids are the most basic organic compounds involved in crucial physiological activities
and are widely found in plants, animals and microorganisms. Due to the anti-inflammatory …

Aryl hydrocarbon receptor antagonism and its role in rheumatoid arthritis

NT Nguyen, T Nakahama, CH Nguyen… - Journal of …, 2015 - Taylor & Francis
Although rheumatoid arthritis (RA) is the most common autoimmune disease, affecting
approximately 1% of the population worldwide, its pathogenic mechanisms are poorly …

Evaluation of anti-inflammatory properties of Eurycoma longifolia Jack and Eurycoma harmandiana Pierre in vitro cultures and their constituents

J Chaingam, R Choonong… - Food and Agricultural …, 2022 - Taylor & Francis
Eurycoma longifolia Jack (EL) has been used for treating erectile dysfunction, in which
inflammation plays a major role. EL tissue cultures can overcome the shortage of material; …

7‐Methoxy‐(9H‐β‐Carbolin‐1‐il)‐(E)‐1‐Propenoic Acid, a β‐Carboline Alkaloid From Eurycoma longifolia, Exhibits Anti‐Inflammatory Effects by Activating the Nrf2 …

N Hai Dang, YY Choo, N Tien Dat… - Journal of cellular …, 2016 - Wiley Online Library
Eurycoma longifolia is an herbal medicinal plant popularly used in Southeast Asian
countries. In the present study, we show that 7‐methoxy‐(9H‐β‐carbolin‐1‐il)‐(E)‐1 …

[HTML][HTML] Tuning gut microbiota through a probiotic blend in gemcitabine‐treated pancreatic cancer xenografted mice

C Panebianco, F Pisati, M Ulaszewska… - Clinical and …, 2021 - ncbi.nlm.nih.gov
Dear Editor: An increased belief of the therapeutic effect of probiotics has recently risen,
since their consumption, by restoring a healthy gut environment, prevents cancer onset and …