Tandem repeat diseases include the neurodegenerative disorders known as polyglutamine
(polyQ) diseases, caused by CAG repeat expansions in the coding regions of the respective …

Most of the neurodegenerative diseases and aging are associated with reactive oxygen
species (ROS) or other intracellular damaging agents that challenge the genome integrity of …

Background Exposure to general anesthesia (GA) during the postnatal period is associated
with neuroinflammation and long-term neurocognitive impairment in preclinical and clinical …

Ataxia is a neurodegenerative syndrome, which can emerge as a major element of a
disease or represent a symptom of more complex multisystemic disorders. It comprises …

Polyglutamine spinocerebellar ataxias (polyQ SCAs) include SCA1, SCA2, SCA3, SCA6,
SCA7, and SCA17 and constitute a group of adult onset neurodegenerative disorders …

Abstract Spinocerebellar Ataxia Type 17 (SCA17) is the most recently identified member of
the polyglutamine (polyQ) family of disorders, resulting from abnormal CAG/CAA expansion …

Polyglutamine (polyQ) diseases are hereditary neurodegenerative disorders caused by an
abnormal expansion of a trinucleotide CAG repeat in the coding region of their respective …

Abstract Background Spinocerebellar ataxia 17 (SCA17) belongs to the family of
neurodegenerative diseases caused by polyglutamine (polyQ) expansion. In SCA17, polyQ …

Trichomes protect plants against insects, microbes, herbivores, and abiotic damages and
assist seed dispersal. The function of CPR5 genes have been found to be involved in the …

TATA-box binding protein (TBP) is required for every single transcription event in archaea
and eukaryotes. It binds DNA and harbors two repeats with an internal structural symmetry …