The primate fovea: structure, function and development

A Bringmann, S Syrbe, K Görner, J Kacza… - Progress in retinal and …, 2018 - Elsevier
A fovea is a pitted invagination in the inner retinal tissue (fovea interna) that overlies an area
of photoreceptors specialized for high acuity vision (fovea externa). Although the shape of …

Adaptation of the central retina for high acuity vision: cones, the fovea and the avascular zone

JM Provis, AM Dubis, T Maddess, J Carroll - Progress in retinal and eye …, 2013 - Elsevier
Presence of a fovea centralis is directly linked to molecular specification of an avascular
area in central retina, before the fovea (or 'pit') begins to form. Modelling suggests that …

Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development

Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson… - Developmental cell, 2020 - cell.com
The development of single-cell RNA sequencing (scRNA-seq) has allowed high-resolution
analysis of cell-type diversity and transcriptional networks controlling cell-fate specification …

Organization of the human trichromatic cone mosaic

H Hofer, J Carroll, J Neitz, M Neitz… - Journal of …, 2005 - Soc Neuroscience
Using high-resolution adaptive-optics imaging combined with retinal densitometry, we
characterized the arrangement of short-(S), middle-(M), and long-(L) wavelength-sensitive …

Histologic development of the human fovea from midgestation to maturity

A Hendrickson, D Possin, L Vajzovic, CA Toth - American journal of …, 2012 - Elsevier
PURPOSE: To describe the histologic development of the human central retina from fetal
week (Fwk) 22 to 13 years. DESIGN: Retrospective observational case series. METHODS …

Patterning and development of photoreceptors in the human retina

KA Hussey, SE Hadyniak… - Frontiers in cell and …, 2022 - frontiersin.org
Humans rely on visual cues to navigate the world around them. Vision begins with the
detection of light by photoreceptor cells in the retina, a light-sensitive tissue located at the …

Pathophysiology, screening and treatment of ROP: a multi-disciplinary perspective

T Chan-Ling, GA Gole, GE Quinn, SJ Adamson… - Progress in retinal and …, 2018 - Elsevier
The population of infants at risk for retinopathy of prematurity (ROP) varies by world region;
in countries with well developed neonatal intensive care services, the highest risk infants are …

Immunological and aetiological aspects of macular degeneration

PL Penfold, MC Madigan, MC Gillies… - Progress in retinal and eye …, 2001 - Elsevier
Aetiological and immunological aspects of AMD, a leading cause of blindness in Western
countries, have been reviewed. Developmental studies suggest that anatomical features …

Anatomy and development of the macula: specialisation and the vulnerability to macular degeneration

JM Provis, PL Penfold, EE Cornish… - Clinical and …, 2005 - Wiley Online Library
The central retina in primates is adapted for high acuity vision. The most significant
adaptations to neural retina in this respect are: 1. The very high density of cone …

Mechanisms of photoreceptor death and survival in mammalian retina

J Stone, J Maslim, K Valter-Kocsi, K Mervin… - Progress in retinal and …, 1999 - Elsevier
The mammalian retina, like the rest of the central nervous system, is highly stable and can
maintain its structure and function for the full life of the individual, in humans for many …