Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2022 - Google Patents
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence
and, together with a modifying polypeptide, provides for site-specific modification of a target …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2023 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2022 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2024 - Google Patents
HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical group C1C= C2C [C@@ H](O)
CC [C@] 2 (C)[C@@ H] 2 [C@@ H] 1 [C@@ H] 1CC [C@ H]([C@ H](C) CCCC (C) …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2022 - Google Patents
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence
and, together with a modifying polypeptide, provides for site-specific modification of a target …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2022 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2022 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2023 - Google Patents
The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence
and, together with a modifying polypeptide, provides for site-specific modification of a target …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2023 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …

Methods and compositions for RNA-directed target DNA modification and for RNA-directed modulation of transcription

JA Doudna, M Jinek, K Chylinski… - US Patent …, 2023 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
49624232&utm_source= google_patent&utm_medium= platform_link&utm_campaign …