[HTML][HTML] Stapled peptides inhibitors: a new window for target drug discovery

AM Ali, J Atmaj, N Van Oosterwijk, MR Groves… - Computational and …, 2019 - Elsevier
Protein-protein interaction (PPI) is a hot topic in clinical research as protein networking has a
major impact in human disease. Such PPIs are potential drugs targets, leading to the need …

[HTML][HTML] Laboratory diagnosis of Mycoplasma pneumoniae infection

F Daxboeck, R Krause, C Wenisch - Clinical Microbiology and Infection, 2003 - Elsevier
Diagnosis of Mycoplasma pneumoniae infection is challenging due to the fastidious nature
of the pathogen, the considerable seroprevalence, and the possibility of transient …

[HTML][HTML] Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

L Skalniak, KM Zak, K Guzik, K Magiera, B Musielak… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Antibodies targeting the PD-1/PD-L1 immune checkpoint achieved spectacular success in
anticancer therapy in the recent years. In contrast, no small molecules with cellular activity …

Increased richness and diversity of the vaginal microbiota and spontaneous preterm birth

AC Freitas, A Bocking, JE Hill, DM Money… - Microbiome, 2018 - Springer
Background The bacterial community present in the female lower genital tract plays an
important role in maternal and neonatal health. Imbalances in this microbiota have been …

The vaginal microbiome of pregnant women is less rich and diverse, with lower prevalence of Mollicutes, compared to non-pregnant women

AC Freitas, B Chaban, A Bocking, M Rocco, S Yang… - Scientific reports, 2017 - nature.com
The vaginal microbiome plays an important role in maternal and neonatal health.
Imbalances in this microbiota (dysbiosis) during pregnancy are associated with negative …

[图书][B] Practical handbook of microbiology

LH Green, E Goldman - 2021 - books.google.com
Practical Handbook of Microbiology, 4th edition provides basic, clear and concise
knowledge and practical information about working with microorganisms. Useful to anyone …

Detection of Mycoplasma in cell cultures

L Young, J Sung, G Stacey, JR Masters - Nature protocols, 2010 - nature.com
Mycoplasma is a prokaryotic organism that is a frequent and occult contaminant of cell
cultures. This organism can modify many aspects of cell physiology, rendering experiments …

[HTML][HTML] Intestinal microbiota determine severity of myocardial infarction in rats

VY Lam, J Su, S Koprowski, A Hsu, JS Tweddell… - The FASEB …, 2012 - ncbi.nlm.nih.gov
Signals from the intestinal microbiota are important for normal host physiology; alteration of
the microbiota (dysbiosis) is associated with multiple disease states. We determined the …

CA-170–a potent small-molecule PD-L1 inhibitor or not?

B Musielak, J Kocik, L Skalniak, K Magiera-Mularz… - Molecules, 2019 - mdpi.com
CA-170 is currently the only small-molecule modulator in clinical trials targeting PD-L1 and
VISTA proteins–important negative checkpoint regulators of immune activation. The reported …

Male–killing Wolbachia in two species of insect

GDD Hurst, FM Jiggins… - … of the Royal …, 1999 - royalsocietypublishing.org
The inherited bacterium Wolbachia spreads through the manipulation of host reproduction,
and has been suggested to be an important factor in arthropod evolution, from host …