Mitochondrial biomarkers for airborne particulate matter associated cardiovascular diseases

PK Mishra, P Kaur - Current Opinion in Environmental Science & Health, 2023 - Elsevier
Airborne particulate matter pollution has become a significant global health concern due to
its detrimental effects on human health, including cardiovascular diseases (CVDs) …

The ST2/IL-33 pathway in adult and paediatric heart disease and transplantation

G Brunetti, B Barile, GP Nicchia, F Onorati, GB Luciani… - Biomedicines, 2023 - mdpi.com
ST2 is a member of interleukin 1 receptor family with soluble sST2 and transmembrane
ST2L isoforms. The ligand of ST2 is IL-33, which determines the activation of numerous …

Carboxypeptidase A4 negatively regulates HGS-ETR1/2-induced pyroptosis by forming a positive feedback loop with the AKT signalling pathway

L Wang, R Deng, S Chen, R Tian, M Guo, Z Chen… - Cell Death & …, 2023 - nature.com
Pyroptosis, a mode of inflammatory cell death, has recently gained significant attention.
However, the underlying mechanism remains poorly understood. HGS-ETR1/2 is a …

Inflammation of some visceral sensory systems and autonomic dysfunction in cardiovascular disease

RM Lataro, F Brognara, R Iturriaga, JFR Paton - Autonomic Neuroscience, 2024 - Elsevier
The sensitization and hypertonicity of visceral afferents are highly relevant to the
development and progression of cardiovascular and respiratory disease states. In this …

Causal effects of inflammatory cytokines on cardiovascular diseases: Insights from genetic evidence

Y Chen, A Zhong - Heliyon, 2024 - cell.com
Background The causal relationship between inflammatory cytokines and cardiovascular
diseases (CVDs) has not been fully elucidated. Exploring this relationship between …

Extracellular and intracellular functions of coiled-coil domain containing 3

S Omari, H Lee, J Wang, SX Zeng… - Journal of Molecular Cell …, 2023 - academic.oup.com
Coiled-coil domain containing 3 (CCDC3, also called Favine) is a highly conserved protein
initially identified as a protein secreted from adipocytes and endothelial cells in the vascular …

[HTML][HTML] Ablation of CCDC8 provides cardioprotection against cardiomyocyte apoptosis via TNF signaling pathway in myocardial ischemia reperfusion injury

J Huang, Z Li, W Huang, J He, J Zheng, S Jiang, J Lin… - Life Sciences, 2024 - Elsevier
Aims Myocardial ischemia-reperfusion (I/R) injury induces significant apoptosis and reactive
oxygen species (ROS) accumulation in cardiomyocytes. Coiled-coil domain-containing 8 …

RGS12 is a target of penehyclidine hydrochloride that enhances oxidative stress and ferroptosis in a model of myocardial ischemia/reperfusion injury by inhibiting the …

C Zi, Y Wei, Y Zhu, J Fan - International Journal of …, 2025 - spandidos-publications.com
Regulator of G‑protein signaling 12 (RGS12) is a regulatory factor that is involved in various
physiological processes. However, the role of RGS12 in myocardial ischemia/reperfusion …

Cellular and Molecular Mechanisms Activated by a Left Ventricular Assist Device

A Galeone, C Buccoliero, B Barile, GP Nicchia… - International Journal of …, 2023 - mdpi.com
Left ventricular assist devices (LVADs) represent the final treatment for patients with end-
stage heart failure (HF) not eligible for transplantation. Although LVAD design has been …

Identification of key genes associated with acute myocardial infarction using WGCNA and two-sample mendelian randomization study

X Yang, Y Huang, D Tang, L Yue - Plos one, 2024 - journals.plos.org
Objective Acute myocardial infarction (AMI) is a severe condition with high morbidity and
mortality rates. This study aimed to identify hub genes potentially associated with AMI and …