Surface-induced dissociation mass spectrometry as a structural biology tool

DT Snyder, SR Harvey, VH Wysocki - Chemical reviews, 2021 - ACS Publications
Native mass spectrometry (nMS) is evolving into a workhorse for structural biology. The
plethora of online and offline preparation, separation, and purification methods as well as …

Surface‐induced dissociation: An effective tool to probe structure, energetics and fragmentation mechanisms of protonated peptides

AR Dongré, Á Somogyi… - Journal of mass …, 1996 - Wiley Online Library
The utility of surface‐induced dissociation (SID) to probe the structure, energetics and
fragmentation mechanisms of protonated peptides is discussed and demonstrated. High …

Influence of peptide composition, gas-phase basicity, and chemical modification on fragmentation efficiency: evidence for the mobile proton model

AR Dongré, JL Jones, Á Somogyi… - Journal of the American …, 1996 - ACS Publications
Relative energetics of fragmentation of protonated peptides are investigated by using
electrospray ionization/surface-induced dissociation (ESI/SID) tandem mass spectrometry …

Tandem mass spectrometry: dissociation of ions by collisional activation

AK Shukla, JH Futrell - Journal of mass spectrometry, 2000 - Wiley Online Library
This review presents a brief historical introduction to the development of tandem mass
spectrometry and its principal applications. It is placed in the context of the general …

Internal energy effects in mass spectrometry

K Vékey - Journal of mass spectrometry, 1996 - Wiley Online Library
The internal energy of an ion has a very large effect on the appearance of the mass
spectrum. The first part of this paper gives the theoretical background:(i) dependence of the …

Collisions of ions with surfaces at chemically relevant energies: Instrumentation and phenomena

V Grill, J Shen, C Evans, RG Cooks - Review of Scientific Instruments, 2001 - pubs.aip.org
An overview of gaseous ion/surface collisions is presented, with special emphasis on the
behavior of polyatomic projectile ions at hyperthermal collision energies (1–100 eV) and the …

Infrared spectroscopy and theoretical studies on gas-phase protonated leu-enkephalin and its fragments: direct experimental evidence for the mobile proton

NC Polfer, J Oomens, S Suhai… - Journal of the American …, 2007 - ACS Publications
The gas-phase structures of the protonated pentapeptide Leu-enkephalin and its main
collision-induced dissociation (CID) product ions, b 4 and a 4, are investigated by means of …

Selective gas-phase cleavage at the peptide bond C-terminal to aspartic acid in fixed-charge derivatives of Asp-containing peptides

C Gu, G Tsaprailis, L Breci, VH Wysocki - Analytical Chemistry, 2000 - ACS Publications
This study focuses on the molecular level interpretation of the selective gas-phase cleavage
at aspartic acid residues (Asp) in protonated peptides. A ϕ3P+ CH2C (O)-group (ϕ= 2, 4, 6 …

Collisional activation of peptide ions in FT‐ICR mass spectrometry

J Laskin, JH Futrell - Mass spectrometry reviews, 2003 - Wiley Online Library
Abstract I. Introduction 159 II. Experimental Techniques 160 A. Gas‐Phase Multiple‐
Collision Activation (MCA‐CID) 160 1. On‐Resonance Excitation 160 2. Off‐Resonance …

Surface-induced dissociation of small molecules, peptides, and non-covalent protein complexes

VH Wysocki, KE Joyce, CM Jones… - Journal of the American …, 2011 - ACS Publications
This article provides a perspective on collisions of ions with surfaces, including surface-
induced dissociation (SID) and reactive ion scattering spectrometry (RISS). The content is …