Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also
has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases …

Few microorganisms are as versatile as Escherichia coli. An important member of the
normal intestinal microflora of humans and other mammals, E. coli has also been widely …

The last fifteen years have seen a reemergence of interest in cancer immunosurveillance
and a broadening of this concept into one termed cancer immunoediting. The latter …

Background & Aims: Adherent-invasive Escherichia coli (AIEC) pathovar has been identified
in the intestinal mucosa of patients with Crohn's disease (CD). AIEC reference strain LF82 is …

Engagement of the NKG2D receptor by tumour-associated ligands may promote tumour
rejection by stimulating innate and adaptive lymphocyte responses,,,,. In humans, NKG2D is …

The gastrointestinal tract is a complex ecosystem that associates a resident microbiota and
cells of various phenotypes lining the epithelial wall expressing complex metabolic activities …

Since the first crystal structure determinations of αβ T cell receptors (TCRs) bound to class I
MHC-peptide (pMHC) antigens in 1996, a sizable database of 24 class I and class II …

According to present concepts, innate immunity is regulated by receptors that determine
danger levels by responding to molecules that are associated with infection or cellular …

Cellular transformation and tumor development result from an accumulation of mutational
and epigenetic changes that alter normal cell growth and survival pathways. For the last 100 …

Despite advances in the diagnostic and therapeutic modalities, the prognosis of several
solid tumor malignancies remains poor. Different factors associated with solid tumors …