MYB oncoproteins: emerging players and potential therapeutic targets in human cancer
Y Cicirò, A Sala - Oncogenesis, 2021 - nature.com
MYB transcription factors are highly conserved from plants to vertebrates, indicating that
their functions embrace fundamental mechanisms in the biology of cells and organisms. In …
their functions embrace fundamental mechanisms in the biology of cells and organisms. In …
The DREAM complex: master coordinator of cell cycle-dependent gene expression
S Sadasivam, JA DeCaprio - Nature Reviews Cancer, 2013 - nature.com
The dimerization partner, RB-like, E2F and multi-vulval class B (DREAM) complex provides
a previously unsuspected unifying role in the cell cycle by directly linking p130, p107, E2F …
a previously unsuspected unifying role in the cell cycle by directly linking p130, p107, E2F …
MYBL2 amplification in breast cancer: molecular mechanisms and therapeutic potential
R Bayley, C Ward, P Garcia - Biochimica et Biophysica Acta (BBA)-Reviews …, 2020 - Elsevier
The MYBL2 gene, also known as B-MYB, is essential to regulate vital cellular processes
including cell proliferation, differentiation and DNA repair. Changes in these pathways can …
including cell proliferation, differentiation and DNA repair. Changes in these pathways can …
The MYBL2–CCL2 axis promotes tumor progression and resistance to anti-PD-1 therapy in ovarian cancer by inducing immunosuppressive macrophages
B Pan, T Wan, Y Zhou, S Huang, L Yuan, Y Jiang… - Cancer Cell …, 2023 - Springer
Background An immunosuppressive tumor microenvironment in ovarian cancer facilitates
tumor progression and resistance to immunotherapy. The function of MYB Proto-Oncogene …
tumor progression and resistance to immunotherapy. The function of MYB Proto-Oncogene …
Overexpression of MYBL2 promotes proliferation and migration of non-small-cell lung cancer via upregulating NCAPH
YC Xiong, J Wang, Y Cheng, XY Zhang… - Molecular and cellular …, 2020 - Springer
Abstract MYB Proto-Oncogene Like 2 (MYBL2) is a highly conserved member of the Myb
family of transcription factors and plays a critical role in regulating cell proliferation and …
family of transcription factors and plays a critical role in regulating cell proliferation and …
[HTML][HTML] Genetic characterization of acquired aplastic anemia by targeted sequencing
M Heuser, C Schlarmann, V Dobbernack… - …, 2014 - ncbi.nlm.nih.gov
M: male; F: female; SAA: severe aplastic anemia; VSAA: very severe aplastic anemia; MAA:
moderate aplastic anemia; ATG: anti-thymocyte globulin; CSA: ciclosporin; alloHSCT …
moderate aplastic anemia; ATG: anti-thymocyte globulin; CSA: ciclosporin; alloHSCT …
UBE2C Is a Transcriptional Target of the Cell Cycle Regulator FOXM1
FOXM1 (forkhead box protein M1) is a transcription factor that participates in all stages of
tumor development, mainly through the control of cell cycle and proliferation, regulating the …
tumor development, mainly through the control of cell cycle and proliferation, regulating the …
B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development
The B-myb (MYBL2) gene is a member of the MYB family of transcription factors and is
involved in cell cycle regulation, DNA replication, and maintenance of genomic integrity …
involved in cell cycle regulation, DNA replication, and maintenance of genomic integrity …
Haploinsufficient Transcription Factors in Myeloid Neoplasms
TC Martinez, ME McNerney - Annual Review of Pathology …, 2024 - annualreviews.org
Many transcription factors (TFs) function as tumor suppressor genes with heterozygous
phenotypes, yet haploinsufficiency generally has an underappreciated role in neoplasia …
phenotypes, yet haploinsufficiency generally has an underappreciated role in neoplasia …
Adverse prognostic value of MYBL2 overexpression and association with microRNA-30 family in acute myeloid leukemia patients
O Fuster, M Llop, S Dolz, P García, E Such, M Ibáñez… - Leukemia research, 2013 - Elsevier
The MYBL2 gene encodes a transcription factor implicated in cell proliferation and
maturation whose amplification or overexpression has been associated with different human …
maturation whose amplification or overexpression has been associated with different human …