The Transport Protein Particle (TRAPP) complexes are highly conserved multisubunit
complexes that act as nucleotide exchange factors (GEFs) for Rab GTPases. They act in …

Correct localization of Rab GTPases in cells is critical for proper function in membrane
trafficking. Guanine‐nucleotide exchange factors (GEFs) act as the primary determinants of …

The highly evolutionarily conserved transport protein particle (TRAPP) complexes (TRAPP II
and III) perform fundamental roles in subcellular trafficking pathways. Here we identified …

Rab1 and Rab11 are essential regulators of the eukaryotic secretory and endocytic
recycling pathways. The transport protein particle (TRAPP) complexes activate these …

Mutations of the human TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9
(TRAPPC9) cause a neurodevelopmental disorder characterised by microcephaly and …

Highly conserved transport protein particle (TRAPP) complexes regulate subcellular
trafficking pathways. Accurate protein trafficking has been increasingly recognized to be …

The formation of complexes between Rab11 and its effectors regulates multiple aspects of
membrane trafficking, including recycling and ciliogenesis. WD repeat–containing protein 44 …

Membrane-enclosed organelles are defining features of eukaryotes in distinguishing these
organisms from prokaryotes. Specification of distinct membranes is critical to assemble and …

Trafficking protein particle (TRAPP) is well reported to play a role in the trafficking of protein
products within the Golgi and endoplasmic reticulum. Dysfunction in TRAPP has been …

Abstract Transport Protein Particle complexes (TRAPP) are evolutionarily conserved
regulators of membrane trafficking, with this mediated by their guanine nucleotide exchange …