Rafting on the evidence for lipid raft-like domains as hubs triggering environmental toxicants' cellular effects

D Marques-da-Silva, R Lagoa - Molecules, 2023 - mdpi.com
The plasma membrane lipid rafts are cholesterol-and sphingolipid-enriched domains that
allow regularly distributed, sub-micro-sized structures englobing proteins to …

Macrophage inflammarafts in atherosclerosis

S Li, JM Navia-Pelaez, SH Choi… - Current opinion in …, 2023 - journals.lww.com
Macrophage inflammarafts in atherosclerosis : Current Opinion in Lipidology Macrophage
inflammarafts in atherosclerosis : Current Opinion in Lipidology Log in or Register Subscribe to …

Targeted nanoparticles triggered by plaque microenvironment for atherosclerosis treatment through cascade effects of reactive oxygen species scavenging and anti …

X Luo, M Zhang, W Dai, X Xiao, X Li, Y Zhu… - Journal of …, 2024 - Springer
Inflammatory factors and reactive oxygen species (ROS) are risk factors for atherosclerosis.
Many existing therapies use ROS-sensitive delivery systems to alleviate atherosclerosis …

[HTML][HTML] Early hyperlipidemia triggers metabolomic reprogramming with increased SAH, increased acetyl-CoA-cholesterol synthesis, and decreased glycolysis

K Xu, F Saaoud, Y Shao, Y Lu, S Wu, H Zhao, K Chen… - Redox Biology, 2023 - Elsevier
To identify metabolomic reprogramming in early hyperlipidemia, unbiased metabolome was
screened in four tissues from ApoE−/− mice fed with high fat diet (HFD) for 3 weeks. 30, 122 …

Functional role of Ash2l in oxLDL induced endothelial dysfunction and atherosclerosis

Z Su, J Wang, C Xiao, W Zhong, J Liu, X Liu… - Cellular and Molecular …, 2024 - Springer
Endothelial injury and dysfunction in the artery wall fuel the process of atherosclerosis. As a
key epigenetic regulator, Ash2l (Absent, small, or homeotic-Like 2) is involved in regulating …

Cannabidiol and Cannabigerol Modify the Composition and Physicochemical Properties of Keratinocyte Membranes Exposed to UVA

A Wroński, I Dobrzyńska, S Sękowski, W Łuczaj… - International Journal of …, 2023 - mdpi.com
The action of UVA radiation (both that derived from solar radiation and that used in the
treatment of skin diseases) modifies the function and composition of keratinocyte …

[HTML][HTML] Mitigating Vascular Inflammation by Mimicking AIBP Mechanisms: A New Therapeutic End for Atherosclerotic Cardiovascular Disease

JD Kim, A Jain, L Fang - International Journal of Molecular Sciences, 2024 - mdpi.com
Atherosclerosis, characterized by the accumulation of lipoproteins and lipids within the
vascular wall, underlies a heart attack, stroke, and peripheral artery disease. Endothelial …

AIBP: A New Safeguard against Glaucomatous Neuroinflammation

S Choi, SH Choi, T Bastola, Y Park, J Oh, KY Kim… - Cells, 2024 - mdpi.com
Glaucoma is a group of ocular diseases that cause irreversible blindness. It is characterized
by multifactorial degeneration of the optic nerve axons and retinal ganglion cells (RGCs) …

TNF-α/IL-1β/IL-1α/IL-12 inflammatory cytokine axes coupled with TLR1/TLR3/TLR5/MYD88 immune signaling pathway over-activation contribute to simultaneous …

W Zhou, X Li, H Zhou, Y Hu, Y Chen, D Guo - Cytokine, 2025 - Elsevier
Background It remains difficult to evaluate the risk factors for concomitant carotid artery as
well as coronary artery diseases in elderly patients. The aim of this research was to …

[HTML][HTML] AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer's disease

YS Kim, SH Choi, KY Kim, JM Navia-Pelaez… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Microglia-driven neuroinflammation plays an important role in the development of
Alzheimer's disease (AD). Microglia activation is accompanied by the formation and chronic …