Tactile sensory information from facial whiskers provides nocturnal tunnel-dwelling rodents,
including mice and rats, with important spatial and textural information about their immediate …

Neuronal activity has been shown to be essential for the proper formation of neuronal
circuits, affecting developmental processes like neurogenesis, migration, programmed cell …

To decipher neural circuits underlying brain functions, viral tracers are widely applied to map
input and output connectivity of neuronal populations. Despite the successful application of …

Comprehensive knowledge of the brain's wiring diagram is fundamental for understanding
how the nervous system processes information at both local and global scales. However …

Here we describe an automated method, named serial two-photon (STP) tomography, that
achieves high-throughput fluorescence imaging of mouse brains by integrating two-photon …

In the rodent vibrissal system, active sensation and sensorimotor integration are mediated in
part by connections between barrel cortex and vibrissal motor cortex. Little is known about …

Neocortex, the neuronal structure at the base of the remarkable cognitive skills of mammals,
is a layered sheet of neuronal tissue composed of juxtaposed and interconnected columns …

In the mammalian neocortex, segregated processing streams are thought to be important for
forming sensory representations of the environment,, but how local information in primary …

Neocortical areas are believed to be organized into vertical modules, the cortical columns,
and the horizontal layers 1–6. In the somatosensory barrel cortex these columns are defined …

Classical studies of mammalian movement control define a prominent role for the primary
motor cortex. Investigating the mouse whisker system, we found an additional and equally …