Bacteria, similar to most organisms, have a love–hate relationship with metals: a specific
metal may be essential for survival yet toxic in certain forms and concentrations. Metal ions …

Ferrocene derivatives have attracted significant interest as anticancer, antibacterial,
antifungal and antiparasitic drug candidates. Discovered in the 1990s, the two most …

Metal ions play important roles in biological processes, 1 and the field of knowledge
concerned with the application of inorganic chemistry to therapy or diagnosis of disease is …

Despite current developments in therapeutics focusing on biotechnologically-oriented
species, the unflagging utility of small molecules or peptides in medicine is still producing …

Schistosomiasis, a major neglected tropical disease, affects more than 250 million people
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel …

Metallodrugs offer potential for unique mechanisms of drug action based on the choice of
the metal, its oxidation state, the types and number of coordinated ligands and the …

The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

With the widespread rise of antimicrobial resistance, most traditional sources for new drug
compounds have been explored intensively for new classes of antibiotics. Meanwhile, metal …

Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Short antimicrobial peptides rich in arginine (R) and tryptophan (W) interact with
membranes. To learn how this interaction leads to bacterial death, we characterized the …