Principles of pain management

BB Hogans - CONTINUUM: Lifelong Learning in Neurology, 2024 - journals.lww.com
Principles of Pain Management : CONTINUUM: Lifelong Learning in Neurology Account
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Pediatric erythromelalgia from multidisciplinary perspectives: a scoping review

DD Ocay, M Graziano Maloney, G D'Souza… - Pediatric …, 2025 - nature.com
Erythromelalgia is a rare, chronic pain disorder characterized by the triad of intense burning
sensation, warmth, and redness, primarily involving the hands and feet, and usually …

Molecular mechanism of choline and ethanolamine transport in humans

K Ri, TH Weng, A Claveras Cabezudo, W Jösting… - Nature, 2024 - nature.com
Human feline leukaemia virus subgroup C receptor-related proteins 1 and 2 (FLVCR1 and
FLVCR2) are members of the major facilitator superfamily. Their dysfunction is linked to …

Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes

MA Bangash, C Cubuk, F Iseppon, R Haroun, C Garcia… - Cell Reports, 2024 - cell.com
The relationship between transcription and protein expression is complex. We identified
polysome-associated RNA transcripts in the somata and central terminals of mouse sensory …

Structural and mechanistic insights into human choline and ethanolamine transport

K Ri, TH Weng, A Claveras Cabezudo, W Jösting, Z Yu… - bioRxiv, 2023 - biorxiv.org
Human feline leukaemia virus subgroup C receptor-related proteins 1 and 2 (FLVCR1 and
2) are major facilitator superfamily transporters from the solute carrier family 49 …

Homozygosity for a Rare PLEC Variant Suggests a Contributory Role in Congenital Insensitivity to Pain

P Kantaputra, T Daroontum, K Kitiyamas… - International Journal of …, 2024 - mdpi.com
Congenital insensitivity to pain is a rare human condition in which affected individuals do not
experience pain throughout their lives. This study aimed to identify the molecular etiology of …

Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus

F Bertino, D Mukherjee, M Bonora, C Bagowski… - Cell Reports …, 2024 - cell.com
Congenital hydrocephalus (CH), occurring in approximately 1/1,000 live births, represents
an important clinical challenge due to the limited knowledge of underlying molecular …

Unearthing FLVCR1a: tracing the path to a vital cellular transporter

V Fiorito, E Tolosano - Cellular and Molecular Life Sciences, 2024 - Springer
Abstract The Feline Leukemia Virus Subgroup C Receptor 1a (FLVCR1a) is a member of the
SLC49 Major Facilitator Superfamily of transporters. Initially recognized as the receptor for …

Optical genome mapping identifies a homozygous deletion in the non-coding region of the SCN9A gene in individuals from the same family with congenital …

A Boughalem, V Ciorna-Monferrato, N Sloboda… - Frontiers in …, 2024 - frontiersin.org
We report an index patient with complete insensitivity to pain and a history of painless
fractures, joint hypermobility, and behavioral problems. The index patient descends from a …

Spectrinopathies in rare neurological and neuromuscular diseases: large-scale efforts towards the identification of novel molecular causes

L Van de Vondel - 2024 - repository.uantwerpen.be
Rare inherited neurological and neuromuscular diseases affect the central nervous system,
peripheral nervous system, and skeletal muscles. About 80% of rare diseases are estimated …