As the scientific enterprise has grown in size and diversity, we need empirical evidence on
the research process to test and apply interventions that make it more efficient and its results …

The idea of “date” and “party” hubs has been influential in the study of protein–protein
interaction networks. Date hubs display low co-expression with their partners, whilst party …

Because multiple drugs act within the context of the regulatory networks in which drug
targets and disease gene products function, module-designed studies are becoming …

Over the last decade there has been an increasing interest in semi-supervised clustering.
Several studies have suggested that even a small amount of supervised information can …

Background Cell responses to environmental stimuli are usually organized as relatively
separate responsive gene modules at the molecular level. Identification of responsive gene …

Background Ovarian cancer is a leading cause of the death from gynecologic malignancies.
Hypoxia is closely related to the malignant growth of cells. However, the molecular …

Background As playing important roles in gene regulation, microRNAs (miRNAs) are
believed as indispensable involvers in the pathogenesis of myocardial infarction (MI) that …

Module identification is a frequently used approach for mining local structures with more
significance in global networks. Recently, a wide variety of bilayer networks are emerging to …

The present study aimed to elucidate key molecular mechanisms in the progression of
diffuse intrinsic pontine glioma (DIPG). The gene expression profile GSE50021, which …

Growth performance and meat quality are important traits for pig production. The aim of the
present study was to investigate the molecular mechanisms underlying growth performance …