Hydrogel interfaces for merging humans and machines

H Yuk, J Wu, X Zhao - Nature Reviews Materials, 2022 - nature.com
The last few decades have witnessed unprecedented convergence between humans and
machines that closely operate around the human body. Despite these advances, traditional …

Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

[HTML][HTML] Walking naturally after spinal cord injury using a brain–spine interface

H Lorach, A Galvez, V Spagnolo, F Martel, S Karakas… - Nature, 2023 - nature.com
A spinal cord injury interrupts the communication between the brain and the region of the
spinal cord that produces walking, leading to paralysis,. Here, we restored this …

Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics

Y Jiang, Z Zhang, YX Wang, D Li, CT Coen, E Hwaun… - Science, 2022 - science.org
Intrinsically stretchable bioelectronic devices based on soft and conducting organic
materials have been regarded as the ideal interface for seamless and biocompatible …

Activity-dependent spinal cord neuromodulation rapidly restores trunk and leg motor functions after complete paralysis

A Rowald, S Komi, R Demesmaeker, E Baaklini… - Nature medicine, 2022 - nature.com
Epidural electrical stimulation (EES) targeting the dorsal roots of lumbosacral segments
restores walking in people with spinal cord injury (SCI). However, EES is delivered with …

Regulation of axonal regeneration after mammalian spinal cord injury

B Zheng, MH Tuszynski - Nature Reviews Molecular Cell Biology, 2023 - nature.com
One hundred years ago, Ramón y Cajal, considered by many as the founder of modern
neuroscience, stated that neurons of the adult central nervous system (CNS) are incapable …

Epidural stimulation of the cervical spinal cord for post-stroke upper-limb paresis

MP Powell, N Verma, E Sorensen, E Carranza… - Nature medicine, 2023 - nature.com
Cerebral strokes can disrupt descending commands from motor cortical areas to the spinal
cord, which can result in permanent motor deficits of the arm and hand. However, below the …

Biodegradation of microplastics: Better late than never

S Miri, R Saini, SM Davoodi, R Pulicharla, SK Brar… - Chemosphere, 2022 - Elsevier
Plastics use is growing due to its applications in the economy, human health and aesthetics.
The major plastic particles in the form of microplastics (MPs) released into the environment …

A spinal cord neuroprosthesis for locomotor deficits due to Parkinson's disease

T Milekovic, EM Moraud, N Macellari, C Moerman… - Nature Medicine, 2023 - nature.com
People with late-stage Parkinson's disease (PD) often suffer from debilitating locomotor
deficits that are resistant to currently available therapies. To alleviate these deficits, we …

[HTML][HTML] An integrated brain-machine interface platform with thousands of channels

E Musk - Journal of medical Internet research, 2019 - jmir.org
Brain-machine interfaces hold promise for the restoration of sensory and motor function and
the treatment of neurological disorders, but clinical brain-machine interfaces have not yet …