Skin cancer pathobiology at a glance: a focus on imaging techniques and their potential for improved diagnosis and surveillance in clinical cohorts

EG Dobre, M Surcel, C Constantin, MA Ilie… - International Journal of …, 2023 - mdpi.com
Early diagnosis is essential for completely eradicating skin cancer and maximizing patients'
clinical benefits. Emerging optical imaging modalities such as reflectance confocal …

Burden and risk factors of brain metastases in melanoma: a systematic literature review

XL Tan, A Le, H Tang, M Brown, E Scherrer, J Han… - Cancers, 2022 - mdpi.com
Simple Summary Brain metastases are common with severe consequences in patients with
melanoma. We conducted a systematic literature review to evaluate the proportion of …

Melanoma Brain Metastases: A Retrospective Analysis of Prognostic Factors and Efficacy of Multimodal Therapies

V Internò, MC Sergi, ME Metta, M Guida, P Trerotoli… - Cancers, 2023 - mdpi.com
Simple Summary The treatment strategies of patients with melanoma brain metastases are
continually evolving, although this remains a poor prognostic subset. We report a real-life …

[HTML][HTML] Brain metastasis and survival outcomes after first-line therapy in metastatic melanoma: a multicenter DeCOG study on 1704 patients from the prospective skin …

C Franklin, P Mohr, L Bluhm, F Meier… - … for ImmunoTherapy of …, 2023 - ncbi.nlm.nih.gov
Background Despite the availability of effective systemic therapies, a significant number of
advanced melanoma patients develops brain metastases. This study investigated …

[HTML][HTML] The meaning of screening: detection of brain metastasis in the adjuvant setting for stage III melanoma

S Derks, K de Joode, E Mulder, LS Ho, A Joosse… - ESMO open, 2022 - Elsevier
Background The incidence of melanoma is increasing and 37% of patients with metastatic
melanoma eventually have brain metastasis (BM). Currently, there is no consensus on …

Characterizing metastatic uveal melanoma patients who develop symptomatic brain metastases

AZ Wei, M Uriel, A Porcu, MP Manos… - Frontiers in …, 2022 - frontiersin.org
Metastatic uveal melanoma (mUM) is an advanced ocular malignancy characterized by a
hepatotropic pattern of spread. As the incidence of brain metastases (BM) in mUM patients …

Value of screening and follow‐up brain MRI scans in patients with metastatic melanoma

AC Eggen, TT Wind, I Bosma, MCA Kramer… - Cancer …, 2021 - Wiley Online Library
Background Novel treatments make long‐term survival possible for subsets of patients with
melanoma brain metastases. Brain magnetic resonance imaging (MRI) may aid in early …

Risk and tropism of central nervous system (CNS) metastases in patients with stage II and III cutaneous melanoma

P Johannet, M Simons, Y Qian, N Azmy, JM Mehnert… - Cancer, 2022 - Wiley Online Library
Background Recent data suggest that patients with stage III melanoma are at high risk for
developing central nervous system (CNS) metastases. Because a subset of patients with …

Brain metastases in adult patients with melanoma of unknown primary in the Netherlands (2011–2020)

CS Padilla, VKY Ho, T Mooijenkind… - Journal of Neuro …, 2023 - Springer
Background Although patients with melanoma of unknown primary (MUP) have a better
prognosis than similar-staged melanoma patients with known primary, the occurrence of …

Management of melanoma central nervous system metastases

P Rutkowski, D Kiprian, T Świtaj… - Oncology in Clinical …, 2024 - journals.viamedica.pl
Melanoma is the third most frequent malignancy (after breast and lung cancers) that causes
metastases in the central nervous system (CNS). It is one of the 20 most common human …