DNA molecules in mitochondria, just like those in the nucleus of eukaryotic cells, are
constantly damaged by noxious agents. Eukaryotic cells have developed efficient …

The mismatch repair (MMR) system detects non-Watson–Crick base pairs and strand
misalignments arising during DNA replication and mediates their removal by catalyzing …

The fungal pathogen Candida glabrata has emerged as a major health threat since it readily
acquires resistance to multiple drug classes, including triazoles and/or echinocandins. Thus …

G protein-coupled receptors represent the largest family of membrane receptors that
instigate signalling through nucleotide exchange on heterotrimeric G proteins. Nucleotide …

DNA repair mechanisms are critical for maintaining the integrity of genomic DNA, and their
loss is associated with cancer predisposition syndromes. Studies in Saccharomyces …

DNA mismatch repair (MMR) is a highly conserved genome stabilizing pathway that corrects
DNA replication errors, limits chromosomal rearrangements, and mediates the cellular …

DNA mismatch repair (MMR) corrects mismatched base pairs mainly caused by DNA
replication errors. The fundamental mechanisms and proteins involved in the early reactions …

DNA mismatch repair (MMR) acts to repair mispaired bases resulting from misincorporation
errors during DNA replication and also recognizes mispaired bases in recombination (HR) …

The genome of all organisms is constantly being challenged by endogenous and
exogenous sources of DNA damage. Errors like base: base mismatches or small insertions …

DNA mismatch repair corrects replication errors, thus reducing mutation rates and
microsatellite instability. Genetic defects in this pathway cause Lynch syndrome and various …