Vaccines, like drugs and medical procedures, are increasingly amenable to individualization or personalization, often based on novel data resulting from high throughput “omics” …
A genome-wide association study (GWAS) of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Recent progress in genomics and bioinformatics technologies have allowed for the emergence of immunogenomics field. This intersection of immunology and genetics has …
Many molecular mechanisms that lead to the host antibody response to COVID-19 vaccines remain largely unknown. In this study, we used serum antibody detection combined with …
L Scola, D Ferraro, GL Sanfilippo, S De Grazia, D Lio… - Vaccines, 2023 - mdpi.com
The introduction of anti-SARS-CoV-2 vaccines in late 2020 substantially changed the pandemic picture, inducing effective protection in the population. However, individual …
CK Cote, JD Heffron, SO Bailey, SL Welkos… - Molecular medical …, 2024 - Elsevier
The genus Bacillus is a diverse group of spore-forming bacteria. Bacillus species have implications in both medical and biodefense aspects of microbiology. This chapter attempts …
Interindividual variations in vaccine-induced immune responses are in part due to host genetic polymorphisms in the human leukocyte antigen (HLA) and other gene families. This …
Background The impact of individual genetic and genomic variations on immune responses is an emerging lever investigated in vaccination strategies. In our study, we used genetic …
MJ Newport - Frontiers in immunology, 2015 - frontiersin.org
A number of factors are recognized to influence immune responses to vaccinations including age, gender, the dose, and quality of the antigen used, the number of doses given, the route …