In the adult mammalian brain, more than 250 protein kinases are expressed, but only a few
of these kinases are currently known to enable learning and memory. Based on this …

Highlights•Different neuron types solve different learning/developmental problems.•Different
neuron types exhibit different dendritic and somatic input–output functions.•A diverse set of …

Experience-dependent neuronal plasticity is a fundamental substrate of learning and
memory. Intrinsic excitability is a form of neuronal plasticity that can be altered by learning …

Since the discovery of complex, voltage dependent mechanisms in the dendrites of multiple
neuron types, great effort has been devoted in search of a direct link between dendritic …

Introduction: Protein kinase M zeta (PKMζ) is assumed to be actively involved in retainig
long-term potentiation. The goal of this study was to investigate the role of PKMζ in …

The research carried out in this thesis builds on the pioneering discoveries by Larry Abbott,
Shimon Marom, Eve Marder, and others, who's research provided key insights on the …

Neurological disorders are a group of incurable, chronic disorders of central nervous (CNS)
and peripheral nervous systems. They are characterized by gradual loss of neuronal …

The physical basis of memory storage in the brain, the memory engram, is a long-standing
question in neuroscience, yet an established theory of its realization is still missing. It is only …