Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …

Drug-resistant tuberculosis (TB) poses a significant challenge to the successful treatment
and control of TB worldwide. Resistance to anti-TB drugs has existed since the beginning of …

The apicoplast is an essential plastid organelle found in Plasmodium parasites which
contains several clinically validated antimalarial-drug targets. A chemical rescue screen …

Important pathogens such as Mycobacterium tuberculosis and Plasmodium falciparum, the
causative agents of tuberculosis and malaria, respectively, and plants, utilize the 2 C-methyl …

Isoprenoids, a diverse class of natural products, are present in all living organisms. Their two
universal building blocks are synthesized via two independent pathways: the mevalonate …

Abstract Background Panax ginseng CA Mey is one of famous medicinal herb plant species.
Its major bioactive compounds are various ginsenosides in roots and rhizomes. It is …

The enzymes of the non‐mevalonate pathway for isoprenoid biosynthesis have been
identified as attractive targets with novel modes of action for the development of herbicides …

Combination therapies, where two drugs acting through different mechanisms are
administered simultaneously, are one of the most efficient approaches currently used to treat …

The occurrence and recurrence of mucosal biofilm-related Candida infections, such as oral
and vulvovaginal candidiasis, are serious clinical issues. Vaginal infections caused by …

The emergence of drug-resistant tuberculosis (TB) constitutes a major challenge to TB
control programmes. There is an urgent need to develop effective anti-TB drugs with novel …