Mobile cognition: imaging the human brain in the 'real world'
Cognitive neuroscience studies in humans have enabled decades of impactful discoveries
but have primarily been limited to recording the brain activity of immobile participants in a …
but have primarily been limited to recording the brain activity of immobile participants in a …
Towards real-world generalizability of a circuit for action-stopping
Two decades of cross-species neuroscience research on rapid action-stopping in the
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …
laboratory has provided motivation for an underlying prefrontal–basal ganglia circuit. Here …
Emerging technologies for improved deep brain stimulation
Deep brain stimulation (DBS) is an effective treatment for common movement disorders and
has been used to modulate neural activity through delivery of electrical stimulation to key …
has been used to modulate neural activity through delivery of electrical stimulation to key …
Rhythm and music-based interventions in motor rehabilitation: current evidence and future perspectives
Research in basic and clinical neuroscience of music conducted over the past decades has
begun to uncover music's high potential as a tool for rehabilitation. Advances in our …
begun to uncover music's high potential as a tool for rehabilitation. Advances in our …
Cross-frequency coupling and intelligent neuromodulation
Cross-frequency coupling (CFC) reflects (nonlinear) interactions between signals of different
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …
frequencies. Evidence from both patient and healthy participant studies suggests that CFC …
Freezing of gait in Parkinson's disease reflects a sudden derangement of locomotor network dynamics
Freezing of gait is a disabling symptom of Parkinson's disease that causes a paroxysmal
inability to generate effective stepping. The underlying pathophysiology has recently …
inability to generate effective stepping. The underlying pathophysiology has recently …
Freezing of gait: understanding the complexity of an enigmatic phenomenon
Diverse but complementary methodologies are required to uncover the complex
determinants and pathophysiology of freezing of gait. To develop future therapeutic …
determinants and pathophysiology of freezing of gait. To develop future therapeutic …
[HTML][HTML] Striatal cholinergic interneuron membrane voltage tracks locomotor rhythms in mice
Rhythmic neural network activity has been broadly linked to behavior. However, it is unclear
how membrane potentials of individual neurons track behavioral rhythms, even though …
how membrane potentials of individual neurons track behavioral rhythms, even though …
[HTML][HTML] Toward electrophysiology-based intelligent adaptive deep brain stimulation for movement disorders
Deep brain stimulation (DBS) represents one of the major clinical breakthroughs in the age
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …
of translational neuroscience. In 1987, Benabid and colleagues demonstrated that high …
[HTML][HTML] Beta bursts during continuous movements accompany the velocity decrement in Parkinson's disease patients
Bradykinesia is reported to correlate with subthalamic beta power (13–35 Hz) recorded at
rest in Parkinson's disease (PD). Pilot studies suggest adaptive deep brain stimulation …
rest in Parkinson's disease (PD). Pilot studies suggest adaptive deep brain stimulation …