Extracellular vesicles: a rising star for therapeutics and drug delivery

S Du, Y Guan, A Xie, Z Yan, S Gao, W Li, L Rao… - Journal of …, 2023 - Springer
Extracellular vesicles (EVs) are nano-sized, natural, cell-derived vesicles that contain the
same nucleic acids, proteins, and lipids as their source cells. Thus, they can serve as natural …

Angiotensin-converting enzyme 2 (ACE2): Two decades of revelations and re-evaluation

AJ Turner, NN Nalivaeva - Peptides, 2022 - Elsevier
Abstract Angiotensin-converting enzyme-2, or ACE2, is primarily a zinc-dependent
peptidase and ectoenzyme expressed in numerous cell types and functioning as a …

Epigenetics of SARS-CoV2 (COVID-19)

S Rawat, R Gilhotra, SK Singh, AA Bhat, A Ojha… - Targeting epigenetics in …, 2023 - Springer
The study of genetic differences in gene activity without alterations to DNA sequences is
referred to as “epigenetics.” The focus of this extremely new field of research is on the …

COVID-19 and cancer: insights into their association and influence on genetic and epigenetic landscape

MK Ghosh, S Kumar, KK Ganguly, P Ghosh… - …, 2023 - Taylor & Francis
The COVID-19 outbreak has created disaster globally, and mankind is yet to come in terms
with combating this global menace. Amid this turmoil, immunocompromised individuals like …

[HTML][HTML] SARS-CoV-2 and the Nucleus

M Chen, Y Ma, W Chang - International Journal of Biological …, 2022 - ncbi.nlm.nih.gov
The ongoing COVID-19 pandemic is caused by an RNA virus, SARS-CoV-2. The genome of
SARS-CoV-2 lacks a nuclear phase in its life cycle and is replicated in the cytoplasm …

COVID-19 and Post-Acute COVID-19 Syndrome: From Pathophysiology to Novel Translational Applications

P Ambrosino, A Lanzillo, M Maniscalco - Biomedicines, 2021 - mdpi.com
Biomedicines | Free Full-Text | COVID-19 and Post-Acute COVID-19 Syndrome: From
Pathophysiology to Novel Translational Applications Next Article in Journal / Special Issue …

Epigenetic targets and pathways linked to SARS-CoV-2 infection and pathology

AA Rabaan, M Aljeldah, BRA Shammari, RA Alsubki… - Microorganisms, 2023 - mdpi.com
The scale at which the SARS-CoV-2/COVID-19 pandemic has spread remains enormous.
Provided the genetic makeup of the virus and humans is readily available, the quest for …

A cautionary note on altered pace of aging in the COVID-19 era

MAH Attia - Forensic Science International: Genetics, 2022 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is highly age-dependent due to hi-jacking
the molecular control of the immune cells by the severe acute respiratory syndrome-corona …

Maximization of the Minicircle DNA Vaccine Production Expressing SARS-CoV-2 RBD

C Ventura, D Eusébio, AM Gonçalves… - Biomedicines, 2022 - mdpi.com
Nucleic acid vaccines have been proven to be a revolutionary technology to induce an
efficient, safe and rapid response against pandemics, like the coronavirus disease (COVID …

Epidemiological, cellular, genetic and epigenetic aspects of biosafety

VG Akimkin, VV Zverev… - Vestnik Rossijskoj …, 2024 - journals.rcsi.science
Currently, the problem of biological safety is extremely relevant for all countries of the world
due to the expansion of the spectrum of real and potential threats caused by exposure to …