Measuring intracranial pressure by invasive, less invasive or non-invasive means: limitations and avenues for improvement

KB Evensen, PK Eide - Fluids and Barriers of the CNS, 2020 - Springer
Sixty years have passed since neurosurgeon Nils Lundberg presented his thesis about
intracranial pressure (ICP) monitoring, which represents a milestone for its clinical …

Cerebral autoregulation monitoring in traumatic brain injury: an overview of recent advances in personalized medicine

FA Zeiler, M Aries, M Czosnyka… - Journal of …, 2022 - liebertpub.com
Impaired cerebral autoregulation (CA) in moderate/severe traumatic brain injury (TBI) has
been identified as a strong associate with poor long-term outcomes, with recent data …

The lower limit of reactivity as a potential individualised cerebral perfusion pressure target in traumatic brain injury: a CENTER-TBI high-resolution sub-study analysis

E Beqiri, FA Zeiler, A Ercole, MM Placek, J Tas… - Critical Care, 2023 - Springer
Background A previous retrospective single-centre study suggested that the percentage of
time spent with cerebral perfusion pressure (CPP) below the individual lower limit of …

Brain tissue oxygen monitoring in traumatic brain injury: part I—To what extent does PbtO2 reflect global cerebral physiology?

T Svedung Wettervik, E Beqiri, SY Bögli, M Placek… - Critical Care, 2023 - Springer
Background The primary aim was to explore the association of global cerebral physiological
variables including intracranial pressure (ICP), cerebrovascular reactivity (PRx), cerebral …

[HTML][HTML] Continuous cerebrovascular reactivity monitoring in moderate/severe traumatic brain injury: a narrative review of advances in neurocritical care

FA Zeiler, A Ercole, M Czosnyka, P Smielewski… - British journal of …, 2020 - Elsevier
Impaired cerebrovascular reactivity in adult moderate and severe traumatic brain injury (TBI)
is known to be associated with worse global outcome at 6–12 months. As technology has …

Autoregulatory management in traumatic brain injury: the role of absolute pressure reactivity index values and optimal cerebral perfusion pressure curve shape

T Svedung Wettervik, A Hånell, T Howells… - Journal of …, 2023 - liebertpub.com
The aim of this study was to investigate if the absolute pressure reactivity index (PRx) value
influenced the association between cerebral perfusion pressure (CPP) and outcome and if …

Intracranial pressure-derived cerebrovascular reactivity indices and their critical thresholds: A Canadian high resolution-traumatic brain injury validation study

KY Stein, L Froese, M Sekhon, D Griesdale… - Journal of …, 2024 - liebertpub.com
Current neurointensive care guidelines recommend intracranial pressure (ICP) and cerebral
perfusion pressure (CPP) centered management for moderate-severe traumatic brain injury …

Current state of high-fidelity multimodal monitoring in traumatic brain injury

C Lindblad, R Raj, FA Zeiler, EP Thelin - Acta neurochirurgica, 2022 - Springer
Introduction Multimodality monitoring of patients with severe traumatic brain injury (TBI) is
primarily performed in neuro-critical care units to prevent secondary harmful brain insults …

Association between cerebrovascular reactivity monitoring and mortality is preserved when adjusting for baseline admission characteristics in adult traumatic brain …

FA Zeiler, A Ercole, E Beqiri, M Cabeleira… - Journal of …, 2020 - liebertpub.com
Cerebral autoregulation, as measured using the pressure reactivity index (PRx), has been
related to global patient outcome in adult patients with traumatic brain injury (TBI). To date …

Automated pupillometry as a triage and assessment tool in patients with traumatic brain injury

TY El Ahmadieh, N Bedros, SE Stutzman, D Nyancho… - World neurosurgery, 2021 - Elsevier
Objective Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in young
adults. Automated infrared pupillometry (AIP) has shown promising results in predicting …