Interleukin-4 as a therapeutic target
Abstract Interleukin-4 (IL-4) is a pleiotropic cytokine mainly known for its role in type 2
immunity. Therapies antagonizing or blocking IL-4 activity have been developed to …
immunity. Therapies antagonizing or blocking IL-4 activity have been developed to …
[HTML][HTML] Excretable IR-820 for in vivo NIR-II fluorescence cerebrovascular imaging and photothermal therapy of subcutaneous tumor
Rationale: Cerebrovascular diseases, together with malignancies, still pose a huge threat to
human health nowadays. With the advantages of its high spatial resolution and large …
human health nowadays. With the advantages of its high spatial resolution and large …
Carotenoids in the management of glaucoma: A systematic review of the evidence
DW Lem, DL Gierhart, PG Davey - Nutrients, 2021 - mdpi.com
Primary open-angle glaucoma (POAG) remains a leading cause of irreversible blindness
globally. Recent evidence further substantiates sustained oxidative stress, and …
globally. Recent evidence further substantiates sustained oxidative stress, and …
Cation flux through SUR1-TRPM4 and NCX1 in astrocyte endfeet induces water influx through AQP4 and brain swelling after ischemic stroke
Brain swelling causes morbidity and mortality in various brain injuries and diseases but
lacks effective treatments. Brain swelling is linked to the influx of water into perivascular …
lacks effective treatments. Brain swelling is linked to the influx of water into perivascular …
Hexahydrocurcumin protects against cerebral ischemia/reperfusion injury, attenuates inflammation, and improves antioxidant defenses in a rat stroke model
P Wicha, J Tocharus, A Janyou, J Jittiwat, C Changtam… - PloS one, 2017 - journals.plos.org
The purpose of the present experiment was to investigate whether hexahydrocurcumin
(HHC) attenuates brain damage and improves functional outcome via the activation of …
(HHC) attenuates brain damage and improves functional outcome via the activation of …
A comparative study of variables influencing ischemic injury in the Longa and Koizumi methods of intraluminal filament middle cerebral artery occlusion in mice
The intraluminal filament model of middle cerebral artery occlusion (MCAO) in mice and rats
has been plagued by inconsistency, owing in part to the multitude of variables requiring …
has been plagued by inconsistency, owing in part to the multitude of variables requiring …
Stigmasterol alleviates cerebral ischemia/reperfusion injury by attenuating inflammation and improving antioxidant defenses in rats
Q Liang, J Yang, J He, X Chen, H Zhang… - Bioscience …, 2020 - portlandpress.com
Background/aims: The paper aimed to investigate the effects of Stigmasterol on
inflammatory factors, antioxidant capacity, and apoptotic signaling pathways in brain tissue …
inflammatory factors, antioxidant capacity, and apoptotic signaling pathways in brain tissue …
Deciphering of cerebrovasculatures via ICG-assisted NIR-II fluorescence microscopy
Benefiting from high spatial resolution and large penetration depth, NIR-II (second near-
infrared spectral region, 900–1700 nm) fluorescence imaging based on US Food and Drug …
infrared spectral region, 900–1700 nm) fluorescence imaging based on US Food and Drug …
Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF‑κB, ICAM-1, MMP-9 and caspase-3 expression
W Li, NC Suwanwela… - Molecular medicine …, 2017 - spandidos-publications.com
Reperfusion is the only approved therapy for acute ischemic stroke; however, it can cause
excessive inflammation responses and aggravate brain damage. Therefore, supplementary …
excessive inflammation responses and aggravate brain damage. Therefore, supplementary …
Morin protects the blood–brain barrier integrity against cerebral ischemia reperfusion through anti-inflammatory actions in rats
S Khamchai, W Chumboatong, J Hata, C Tocharus… - Scientific reports, 2020 - nature.com
This study aimed to investigate the effects of morin on cerebral damage and blood–brain
barrier (BBB) integrity in a middle cerebral artery occlusion (MCAO) and reperfusion model …
barrier (BBB) integrity in a middle cerebral artery occlusion (MCAO) and reperfusion model …