Chemical glycoproteomics

KK Palaniappan, CR Bertozzi - Chemical reviews, 2016 - ACS Publications
Chemical tools have accelerated progress in glycoscience, reducing experimental barriers
to studying protein glycosylation, the most widespread and complex form of posttranslational …

Proteomic techniques for characterisation of mesenchymal stem cell secretome

HK Skalnikova - Biochimie, 2013 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent cells with a substantial potential in human
regenerative medicine due to their ability to migrate to sites of injury, capability to suppress …

The in silico human surfaceome

D Bausch-Fluck, U Goldmann… - Proceedings of the …, 2018 - National Acad Sciences
Cell-surface proteins are of great biomedical importance, as demonstrated by the fact that
66% of approved human drugs listed in the DrugBank database target a cell-surface protein …

A mass spectrometric-derived cell surface protein atlas

D Bausch-Fluck, A Hofmann, T Bock, AP Frei… - PloS one, 2015 - journals.plos.org
Cell surface proteins are major targets of biomedical research due to their utility as cellular
markers and their extracellular accessibility for pharmacological intervention. However …

[HTML][HTML] Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints

DF Zielinska, F Gnad, JR Wiśniewski, M Mann - Cell, 2010 - cell.com
N-linked glycosylation is a biologically important protein modification, but only a small
fraction of modification sites have been mapped. We developed a" filter aided sample …

Glycopeptide enrichment and separation for protein glycosylation analysis

S Ongay, A Boichenko, N Govorukhina… - Journal of separation …, 2012 - Wiley Online Library
Protein glycosylation plays key roles in many biological processes. In addition, alterations in
protein glycosylation have been related to different diseases, as well as may affect the …

Isolation of cell surface proteins for mass spectrometry-based proteomics

S Elschenbroich, Y Kim, JA Medin… - Expert review of …, 2010 - Taylor & Francis
Defining the cell surface proteome has profound importance for understanding cell
differentiation and cell–cell interactions, as well as numerous pathogenic abnormalities …

Surface glycoproteins of exosomes shed by myeloid-derived suppressor cells contribute to function

S Chauhan, S Danielson, V Clements… - Journal of proteome …, 2017 - ACS Publications
In this report, we use a proteomic strategy to identify glycoproteins on the surface of
exosomes derived from myeloid-derived suppressor cells (MDSCs), and then test if selected …

Glycoproteomics enabled by tagging sialic acid-or galactose-terminated glycans

TNC Ramya, E Weerapana, BF Cravatt… - …, 2013 - academic.oup.com
In this paper, we present two complementary strategies for enrichment of glycoproteins on
living cells that combine the desirable attributes of “robust enrichment” afforded by covalent …

Aquaporin-3 in keratinocytes and skin: Its role and interaction with phospholipase D2

H Qin, X Zheng, X Zhong, AK Shetty, PM Elias… - Archives of Biochemistry …, 2011 - Elsevier
Aquaporin 3 (AQP3) is an aquaglyceroporin that transports water and glycerol and is
expressed in the epidermis, among other epithelial tissues. We have recently shown that …