Diabetic retinopathy (DR) is a common complication of diabetes and constitutes a major
cause of vision impairment and blindness in the world. DR has long been described …

Different optic neuropathies will benefit from neuro-protective versus neuro-regenerative
approaches. Developing clinically effective treatments for optic nerve disease will require a …

To investigate the neuroprotective effect of brimonidine after retinal ischemia damage on
mouse eye. Glaucoma is an optic neuropathy characterized by retinal ganglion cells (RGCs) …

Melatonin is of great importance for regulating several eye processes, including pressure
homeostasis. Melatonin in combination with agomelatine has been recently reported to …

Cholera toxin subunit B (CTB) and Fluorogold (FG) are two widely utilized retrograde tracers
to assess the number and function of retinal ganglion cells (RGCs). However, the relative …

Glaucoma is a multifactorial optic neuropathy that primarily affecting retinal ganglion cells
(RGC). Brimonidine is an intraocular pressure-lowering drug with reported neuroprotective …

Age-related macular degeneration and specially neovascular age-related macular
degeneration is the leading cause of low vision in developed countries. Even though the …

The ageing process is a multifactorial phenomenon, associated with decreased
physiological and cellular functions and an increased propensity for various degenerative …

Background: glaucoma is the leading cause of irreversible blindness all over the world. The
degree of visual field loss accounts for the severity of the disease and represents the main …

Ischaemia/reperfusion contributes to the pathophysiological process of many retinal
diseases. Previous studies have shown that retinal ischaemia/reperfusion mainly results in …