Several diseases associated with high-altitude exposure affect unacclimated individuals.
These diseases include acute mountain sickness (AMS), high-altitude cerebral edema …

Telomere attrition is considered a hallmark of ageing. Untangling the proximate causes of
telomere attrition may therefore reveal important aspects about the ageing process. In a …

Globally, about 400 million people reside at terrestrial altitudes above 1500 m, and more
than 100 million lowlanders visit mountainous areas above 2500 m annually. The …

It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …

The objectives of the current study were to screen antioxidant lactic acid bacteria (LAB)
strains isolated from traditionally fermented Tibetan yak milk, and to evaluate their probiotic …

Homeostasis between pro-oxidants and anti-oxidants is necessary for aerobic life, which if
perturbed and shifted towards pro-oxidants results in oxidative stress. It is generally agreed …

Tibetan nomads have lived since ancient times in the unique and harsh environment of the
Qinghai-Tibetan Plateau with average altitudes over 4000 m. These people have been able …

Eleutheroside E (EE) is a primary active component of Acanthopanax senticosus, which has
been reported to inhibit the expression of inflammatory genes, but the underlying …

The placenta responds to adverse environmental conditions by adapting its capacity for
substrate transfer to maintain fetal growth and development. Early-onset hypoxia effects on …

Various strategies can be employed to prevent and manage altitude illnesses, including
habituation, oxygenation, nutritional support, and medication. Nevertheless, the utilization of …