In-cell NMR: Why and how?

FX Theillet, E Luchinat - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging

BS Saini, JRT Darby, S Portnoy, L Sun… - The Journal of …, 2020 - Wiley Online Library
Key points Human fetal Doppler ultrasound and invasive blood gas measurements obtained
by cordocentesis or at the time of delivery reveal similarities with sheep (an extensively used …

d‐glucose weighted chemical exchange saturation transfer (glucoCEST)‐based dynamic glucose enhanced (DGE) MRI at 3T: early experience in healthy volunteers …

X Xu, AA Sehgal, NN Yadav, J Laterra… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose Dynamic glucose enhanced (DGE) MRI has shown potential for imaging glucose
delivery and blood–brain barrier permeability at fields of 7T and higher. Here, we evaluated …

The impact of isoflurane anesthesia on brain metabolism in mice: An MRI and electroencephalography study

Z Wei, SE Roh, X Yang, W Wang, J Wang… - NMR in …, 2024 - Wiley Online Library
Isoflurane is one of the most widely used anesthetic agents in rodent imaging studies.
However, the impact of isoflurane on brain metabolism has not been fully characterized to …

Hyperpolarized MRI, functional MRI, MR spectroscopy and CEST to provide metabolic information in vivo

PCM van Zijl, K Brindle, H Lu, PB Barker… - Current opinion in …, 2021 - Elsevier
Access to metabolic information in vivo using magnetic resonance (MR) technologies has
generally been the niche of MR spectroscopy (MRS) and spectroscopic imaging (MRSI) …

[HTML][HTML] Morphology of perivascular spaces and enclosed blood vessels in young to middle-aged healthy adults at 7T: Dependences on age, brain region, and …

X Zong, C Lian, J Jimenez, K Yamashita, D Shen… - Neuroimage, 2020 - Elsevier
Perivascular spaces (PVSs) are fluid-filled spaces surrounding penetrating blood vessels in
the brain and are an integral pathway of the glymphatic system. A PVS and the enclosed …

Single and combined neuroimaging techniques for Alzheimer's disease detection

M Amini, MM Pedram, A Moradi… - Computational …, 2021 - Wiley Online Library
Alzheimer's disease (AD) consists of the gradual process of decreasing volume and quality
of neuron connection in the brain, which consists of gradual synaptic integrity and loss of …

Quantification of whole‐organ individual and bilateral renal metabolic rate of oxygen

RS Deshpande, MC Langham, H Lee… - Magnetic …, 2024 - Wiley Online Library
Purpose Renal metabolic rate of oxygen (rMRO2) is a potentially important biomarker of
kidney function. The key parameters for rMRO2 quantification include blood flow rate (BFR) …

[HTML][HTML] Effect of motion, cortical orientation and spatial resolution on quantitative imaging of cortical R2* and magnetic susceptibility at 0.3 mm in-plane resolution at 7 …

P van Gelderen, X Li, JA de Zwart, ES Beck, SV Okar… - NeuroImage, 2023 - Elsevier
MR images of the effective relaxation rate R 2* and magnetic susceptibility χ derived from
multi-echo T 2*-weighted (T 2* w) MRI can provide insight into iron and myelin distributions …