Baculovirus: an insect-derived vector for diverse gene transfer applications

KJ Airenne, YC Hu, TA Kost, RH Smith, RM Kotin… - Molecular Therapy, 2013 - cell.com
Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …

Introduction to viral vectors

JN Warnock, C Daigre, M Al-Rubeai - Viral vectors for gene therapy …, 2011 - Springer
Viral vector is the most effective means of gene transfer to modify specific cell type or tissue
and can be manipulated to express therapeutic genes. Several virus types are currently …

Baculovirus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications

CY Chen, CY Lin, GY Chen, YC Hu - Biotechnology advances, 2011 - Elsevier
Baculovirus infects insects in nature and is non-pathogenic to humans, but can transduce a
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …

Baculoviral vectors for gene delivery: a review

YC Hu - Current gene therapy, 2008 - ingentaconnect.com
Baculovirus has emerged as a novel vector for in vivo and in vitro gene delivery. In addition,
the applications of baculovirus-mediated gene transfer have been explosively expanded to …

Baculovirus vectors for gene therapy

YC Hu - Advances in virus research, 2006 - Elsevier
Since the discovery that baculoviruses can efficiently transduce mammalian cells,
baculoviruses have been extensively studied as potential vectors for both in vitro and in vivo …

Baculovirus GP64-mediated entry into mammalian cells

C Kataoka, Y Kaname, S Taguwa, T Abe… - Journal of …, 2012 - Am Soc Microbiol
The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) serves as
an efficient viral vector, not only for abundant gene expression in insect cells, but also for …

PCR primer design

A Apte, S Daniel - Cold Spring Harbor Protocols, 2009 - cshprotocols.cshlp.org
The objective of a polymerase chain reaction (PCR) is to amplify a specific DNA segment
without any nonspecific by-products. In principle, each physical and chemical component of …

Enhanced baculovirus-mediated transduction of human cancer cells by tumor-homing peptides

AR Mäkelä, H Matilainen, DJ White… - Journal of …, 2006 - Am Soc Microbiol
Tumor cells and vasculature offer specific targets for the selective delivery of therapeutic
genes. To achieve tumor-specific gene transfer, baculovirus tropism was manipulated by …

Baculovirus entry into human hepatoma cells

H Matilainen, J Rinne, L Gilbert, V Marjomäki… - Journal of …, 2005 - Am Soc Microbiol
Autographa californica multiple nucleopolyhedrovirus (AcMNPV), a prototype member of the
Baculoviridae family, has gained increasing interest as a potential vector candidate for …

BacMam expressing highly glycosylated porcine interferon alpha induces robust antiviral and adjuvant effects against foot-and-mouth disease virus in pigs

A Kim, G Lee, JH Hwang, JH Park, MJ Lee… - Journal of …, 2022 - Am Soc Microbiol
Foot-and-mouth disease (FMD) is an acute contagious disease that affects cloven-hoofed
animals and has severe global economic consequences. FMD is most commonly controlled …