Peripheral glia diversity

CB Reed, ML Feltri, ER Wilson - Journal of anatomy, 2022 - Wiley Online Library
Recent years have seen an evolving appreciation for the role of glial cells in the nervous
system. As we move away from the typical neurocentric view of neuroscience, the complexity …

Cell migration and axon guidance at the border between central and peripheral nervous system

TACS Suter, A Jaworski - Science, 2019 - science.org
BACKGROUND In vertebrates, the central and peripheral nervous system (CNS and PNS,
respectively) are segregated at the cellular level. The CNS encompasses the brain and …

Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates

L Faure, Y Wang, ME Kastriti, P Fontanet… - Nature …, 2020 - nature.com
Somatic sensation is defined by the existence of a diversity of primary sensory neurons with
unique biological features and response profiles to external and internal stimuli. However …

Structural decoding of netrin-4 reveals a regulatory function towards mature basement membranes

R Reuten, TR Patel, M McDougall, N Rama… - Nature …, 2016 - nature.com
Netrins, a family of laminin-related molecules, have been proposed to act as guidance cues
either during nervous system development or the establishment of the vascular system. This …

Incorporating combinatorial approaches to encourage targeted neural stem/progenitor cell integration following transplantation in spinal cord injury

K Pieczonka, MG Fehlings - Stem Cells Translational Medicine, 2023 - academic.oup.com
Spinal cord injury (SCI) severely diminishes quality of life and presents patients with a
substantial financial burden. The lack of a curative treatment has guided efforts toward …

Involvement of netrins and their receptors in neuronal migration in the cerebral cortex

S Yamagishi, Y Bando, K Sato - Frontiers in cell and developmental …, 2021 - frontiersin.org
In mammals, excitatory cortical neurons develop from the proliferative epithelium and
progenitor cells in the ventricular zone and subventricular zone, and migrate radially to the …

[HTML][HTML] Whole-genome sequencing identifies potential candidate genes for reproductive traits in pigs

X Li, J Ye, X Han, R Qiao, X Li, G Lv, K Wang - Genomics, 2020 - Elsevier
Reproductive performance is a complex quantitative trait, that is determined by multiple
genes, regulatory pathways and environmental factors. A list of major genes with large effect …

Mutations in the netrin-1 gene cause congenital mirror movements

A Méneret, EA Franz, O Trouillard… - The Journal of …, 2017 - Am Soc Clin Investig
Netrin-1 is a secreted protein that was first identified 20 years ago as an axon guidance
molecule that regulates midline crossing in the CNS. It plays critical roles in various tissues …

CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4

AM Garrett, PJ Bosch, DM Steffen, LC Fuller… - PLoS …, 2019 - journals.plos.org
The mammalian Pcdhg gene cluster encodes a family of 22 cell adhesion molecules, the
gamma-Protocadherins (γ-Pcdhs), critical for neuronal survival and neural circuit formation …

Netrin family: Role for protein isoforms in cancer

CS Bruikman, H Zhang, AM Kemper… - Journal of nucleic …, 2019 - Wiley Online Library
Netrins form a family of secreted and membrane‐associated proteins. Netrins are involved in
processes for axonal guidance, morphogenesis, and angiogenesis by regulating cell …