The impact of the gut microbiome on extra-intestinal autoimmune diseases

E Miyauchi, C Shimokawa, A Steimle… - Nature Reviews …, 2023 - nature.com
The prevalence of autoimmune diseases (ADs) worldwide has rapidly increased over the
past few decades. Thus, in addition to the classical risk factors for ADs, such as genetic …

[HTML][HTML] The influence of evolutionary history on human health and disease

ML Benton, A Abraham, AL LaBella, P Abbot… - Nature Reviews …, 2021 - nature.com
Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

[图书][B] The probiotic planet: Using life to manage life

J Lorimer - 2020 - books.google.com
Assesses a promising new approach to restoring the health of our bodies and our planet
Most of us are familiar with probiotics added to milk or yogurt to improve gastrointestinal …

Paneth cell-derived lysozyme defines the composition of mucolytic microbiota and the inflammatory tone of the intestine

S Yu, I Balasubramanian, D Laubitz, K Tong… - Immunity, 2020 - cell.com
Paneth cells are the primary source of C-type lysozyme, a β-1, 4-N-
acetylmuramoylhydrolase that enzymatically processes bacterial cell walls. Paneth cells are …

Cross-domain and viral interactions in the microbiome

AD Rowan-Nash, BJ Korry, E Mylonakis… - … and Molecular Biology …, 2019 - Am Soc Microbiol
The importance of the microbiome to human health is increasingly recognized and has
become a major focus of recent research. However, much of the work has focused on a few …

[HTML][HTML] Helminth parasites and immune regulation

PH Gazzinelli-Guimaraes, TB Nutman - F1000Research, 2018 - ncbi.nlm.nih.gov
Helminth parasites are complex metazoans that belong to different taxonomic families but
that collectively share the capacity to downregulate the host immune response directed …

Regulation of immunity and allergy by helminth parasites

RM Maizels - Allergy, 2020 - Wiley Online Library
There is increasing interest in helminth parasite modulation of the immune system, both from
the fundamental perspective of the “arms race” between host and parasite, and equally …

Regulatory T‐cells in helminth infection: induction, function and therapeutic potential

MPJ White, CM McManus, RM Maizels - Immunology, 2020 - Wiley Online Library
Helminth parasites infect an alarmingly large proportion of the world's population, primarily
within tropical regions, and their ability to down‐modulate host immunity is key to their …

Targeting the PI3K/Akt signaling pathway in pancreatic β‐cells to enhance their survival and function: an emerging therapeutic strategy for type 1 diabetes

I Camaya, S Donnelly, B O'Brien - Journal of Diabetes, 2022 - Wiley Online Library
Abstract Type 1 diabetes (T1D) is an autoimmune disease caused by the destruction of the
insulin‐producing β‐cells within the pancreas. Islet transplantation represents one cure; …

Global trends in urban agriculture research: A pathway toward urban resilience and sustainability

D Yan, L Liu, X Liu, M Zhang - Land, 2022 - mdpi.com
Urban agriculture has been proposed as an important urban element to deal with the
challenges of food insecurity and environmental deterioration. In order to track current …