Aims: Beta thalassemia is the most common monogenic hereditary hemoglobin disorder,
which poses a major health burden to Sri-Lanka. Regular transfusions of erythrocytes …

Background Iron overload‐induced oxidative stress and transfusion‐acquired hepatitis C
virus (HCV) infection are the main reasons of liver damage in beta thalassemia major (β …

Beta thalassemia is a hereditary hemolytic anemia caused by a defect in the ability of
erythroblasts to synthesize the β chain of hemoglobin. The aims of the current study were to …

Since iron overload is the commonest cause of morbidity and mortality in β thalassemia
major (β-TM), it represents one major target in therapeutic management of the disease. The …

Background: Beta-thalassemia major is a type of inherited blood disease that results in
variable outcomes such as severe anemia due to haemoglobin chains. Recurrent and …

Background: To determine and compare the serum hepcidin levels and conventional
markers of iron status in patients of β-thalassaemia major with controls. Methods: Forty …

Background: Ineffective erythropoiesis is a predominant feature in β-thalassemia major (β-
TM), causing marked erythroid expansion leading to highly raised levels of growth …

Background: Serum Hepcidin level drop is a main feature of chronic hemolytic anemia like β-
thalassemia as an example. It is assumed that Hepcidin is influenced by anemia, iron …

Objective: To determine the effects of iron overload on Height, Body Mass Index (BMI),
Hemoglobin and Serum Ferritin levels in beta thalassemia major patients undergoing …

Aims: To evaluate the prevalence of endocrine complications in beta thalassaemia major
patients in one of thalassaemia treatment units in Sri Lanka. Methods: The patients (n= 40) …