The self-organisation of a fertilised egg to form a blastocyst structure, which consists of three distinct cell lineages (trophoblast, epiblast and hypoblast) arranged around an off-centre …
Y Liu, J He, R Chen, H Liu, J Chen, Y Liu… - Cellular and Molecular …, 2021 - Springer
Human induced pluripotent stem cells (iPSCs) technology has been widely applied to cell regeneration and disease modeling. However, most mechanism of somatic reprogramming …
Z Hu, Z Chen, W Jiang, D Fang, P Peng, S Yao… - Biochemical …, 2023 - Springer
Gastric cancer (GC) is a common malignant tumor, posing a great threat to human's health and life. Previous studies have suggested aberrant expression of long non-coding RNAs …
Y Chen, M Li, Y Wu - Frontiers in Genetics, 2024 - frontiersin.org
The ectopic expression of four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc (OSKM), known as “Yamanaka factors,” can reprogram or stimulate the production of induced …
JA Neira, JV Conrad, M Rusteika… - Frontiers in Cell and …, 2024 - frontiersin.org
Pigs (Sus scrofa) are widely acknowledged as an important large mammalian animal model due to their similarity to human physiology, genetics, and immunology. Leveraging the full …
RPM Lemos, CBDO Matielo, DC Beise, VG Da Rosa… - Biology, 2018 - mdpi.com
Invasive plant species are expected to display high dispersal capacity but low levels of genetic diversity due to the founder effect occurring at each invasion episode …
SK Dhara, BK Sajjanar, J Ghosh - Stem Cells in Veterinary Science, 2022 - Springer
Abstract In 2006, Shinya Yamanaka successfully reprogrammed differentiated mouse somatic cells by ectopic expression of four transcriptionmodulators are needed for …
N WANG, S WANG, Y WANG, Y CAI, F YANG, H WANG - 2017 - journal.hep.com.cn
Sall4 as one of the spalt family members contains several alternative splicing variants, which are differentially expressed and has a key role in maintaining pluripotent stem cells …